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介入再通术改善慢性闭塞性脑血管病变患者认知功能的初步研究
Interventional recanalization improves cognitive function in patients with chronic total cerebrovascular occlusion
- 第三军医大学学报 2017年39卷第6期 页码：564-567
- 作者机构：
1.400038 重庆，第三军医大学西南医院：神经内科
2.400038 重庆，第三军医大学西南医院：心理科
- 作者简介：
[史树贵,E-mail:shishg@yeah.netShi Shugui,E-mail:shishg@yeah.net
- 基金信息：
DOI：10.16016/j.1000-5404.201610036
中图分类号： R741.05;R743;R749.1收稿：2016-10-08，
修回：2016-11-05，
纸质出版：2017-06
- 稿件说明：
移动端阅览
王益, 史树贵, 陈康宁, 等. 介入再通术改善慢性闭塞性脑血管病变患者认知功能的初步研究[J]. 第三军医大学学报, 2017,39(6):564-567.
Yi Wang, Shugui Shi, Kangning Chen, et al. Interventional recanalization improves cognitive function in patients with chronic total cerebrovascular occlusion[J]. Journal of Third Military Medical University, 2017, 39(6): 564-567.
王益, 史树贵, 陈康宁, 等. 介入再通术改善慢性闭塞性脑血管病变患者认知功能的初步研究[J]. 第三军医大学学报, 2017,39(6):564-567. DOI： 10.16016/j.1000-5404.201610036.
Yi Wang, Shugui Shi, Kangning Chen, et al. Interventional recanalization improves cognitive function in patients with chronic total cerebrovascular occlusion[J]. Journal of Third Military Medical University, 2017, 39(6): 564-567. DOI： 10.16016/j.1000-5404.201610036.
摘要
目的
2
观察介入再通术对慢性闭塞性脑血管病变 (chronic total cerebrovascular occlusion，CTO) 患者认知功能的改善情况，并与未进行血管再通的CTO患者进行对比。
方法
2
选择我院2013年5月至2016年5月收治的CTO患者55例，其中介入再通组 (治疗组)21例，非再通组 (对照组)34例，比较术后12、24个月认知功能情况，采用简易智能精神状态检查量表 (mini-mental state examination，MMSE)、蒙特利尔认知功能评分表 (Montreal cognitive assessment，MoCA) 评估患者认知功能。
结果
2
治疗组与对照组患者术前美国国立卫生研究院卒中评分量表 (national institute of health stroke scale，NIHSS) 评分差异有统计学意义 (
P
<
0.05)，而性别、年龄、文化程度、脑血管危险因素、认知功能等基线资料差异没有统计学意义 (
P
>
0.05)。随访期间，两组患者认知功能 (12个月后MMSE、MoCA，24个月后MMSE、MoCA量表评分) 比较差异有统计学意义 (
P
<
0.05
P
<
0.01)。
结论
2
介入再通术可以明显改善CTO患者的认知功能。
Abstract
Objective
2
To investigate the efficacy of interventional recanalization in cognitive function in the patients with chronic total cerebrovascular occlusion (CTO).
Methods
2
Fifty-five patients with CTO admitted in our hospital from May 2013 to May 2016 were analyzed retrospectively
involving 21 recanalization patients as the treatment group and 34 non-recanalization patients as the control group. Mini-mental state examination (MMSE) and Montreal cognitive assessment (MoCA) were used to investigate the cognitive function in the first and second years after recanalization.
Results
2
There was difference in the national institute of health stroke scale (NIHSS) score between the treatment and control groups (4.80±3.76
vs
2.71±2.92
P
<
0.05)
while there was no significant difference in baseline data including gender
age
culture level
cerebrovascular risk factors and cognitive function (
P
>
0.05). In the follow-up period
there wer
e significant differences in the cognitive function between the former and latter groups in MMSE
MoCA in the first year
and MMSE
and MoCA in the second year (
P
<
0.05
P
<
0.01).
Conclusion
2
The interventional recanalization can significantly improve cognitive function of the patients with CTO.
关键词
Keywords
references
陈静, 郝玉曼, 秦新月.颅内动脉粥样硬化性狭窄的研究进展[J].现代临床医学, 2016, 42(1): 18-21, 24. DOI:10.11851/j.issn.1673-1557.2016.01.006
Chen J, Hao Y M, Qin X Y. Advances in intracranial atherosclerotic stenosis[J]. Journal of Modern Clinical Medicine, 2016, 42(1): 18-21, 24. DOI:10.11851/j.issn.1673-1557.2016.01.006
Cheng Y, Wang Y J, Yan J C, et al. Effects of carotid artery stenting on cognitive function in patients with mild cognitive impairment and carotid stenosis[J]. Exp Ther Med, 2013, 5(4): 1019-1024. DOI:10.3892/etm.2013.954
Sussman E, Kellner C, McDowell M, et al. Endovascular Thrombectomy Following Acute Ischemic Stroke: A Single-Center Case Series and Critical Review of the Literature[J]. Brain Sciences, 2013(2): 521-539. DOI:10.3390/brainsci3020521
Thanvi B, Robinson T. Complete occlusion of extracranial internal carotid artery: clinical features, pathophysiology, diagnosis and management[J]. Postgrad Med J, 2007, 83(976): 95-99. DOI:10.1136/pgmj.2006.048041
Horie N, Tateishi Y, Morikawa M, et al. Acute stroke with major intracranial vessel occlusion: Characteristics of cardioembolism and atherosclerosis-related in situ stenosis/occlusion[J]. J Clin Neurosci, 2016, 32: 24-29. DOI:10.1016/j.jocn.2015.12.043
Wang Y, Zhao X, Liu L, et al. Prevalence and outcomes of symptomatic intracranial large artery stenoses and occlusions in China:the Chinese Intracranial Atherosclerosis (CICAS) study[J]. Stroke, 2014, 45(3): 663-669. DOI:10.1161/STROKEAHA.113.003508
Hill M D, Demchuk A M, Frayne R. Noninvasive imaging is improving but digital subtraction angiography remains the gold standard[J]. Neurology, 2007, 68(24): 2057-2058. DOI:10.1212/01.wnl.0000268580.86336.af
Lanari A, Silvestrelli G. Acute and chronic carotid occlusion syndromes[J]. Front Neurol Neurosci, 2012, 30: 185-190. DOI:10.1159/000333639
Xiong Z, Liu C, Wang F, et al. Protective effects of breviscapine on ischemic vascular dementia in rats[J]. Biol Pharm Bull, 2006, 29(9): 1880-1885. DOI:10.1248/bpb.29.1880
李桂岚, 隋汝波, 马贺骥, 等.血管性痴呆患者小脑磁共振波谱改变的临床研究[J].第三军医大学学报, 2016, 38(19): 2186-2189. DOI:10.16016/j.1000-5404.201603069.
Li G L, Sui R B, Ma H J, et al. MR spectroscopic changes of cerebellum in vascular dementia patients[J]. J Third Mil Med Univ, 2016, 38(19): 2186-2189. DOI:10.16016/j.1000-5404.201603069
Radak D, Tanaskovic 'S, Matic 'P, et al. Eversion carotid endarterectomy:our experience after 20 years of carotid surgery and 9897 carotid endarterectomy procedures[J]. Ann Vasc Surg, 2012, 26(7): 924-928. DOI:10.1016/j.avsg.2011.09.011
Powers W J, Clarke W R, Grubb R L Jr, et al. Extracranial-intracranial bypass surgery for stroke prevention in hemodynamic cerebral ischemia: the Carotid Occlusion Surgery Study randomized trial[J]. JAMA, 2011, 306(18): 1983-1992. DOI:10.1001/jama.2011.1610
Guay J, Ochroch E A. Carotid endarterectomy plus medical therapy or medical therapy alone for carotid artery stenosis in symptomatic or asymptomatic patients: a meta-analysis[J]. J Cardiothorac Vasc Anesth, 2012, 26(5): 835-844. DOI:10.1053/j.jvca.2012.01.044
Sakes A, Regar E, Dankelman J, et al. Treating Total Occlusions: Applying Force for Recanalization[J]. IEEE Rev Biomed Eng, 2016, 9: 192-207. DOI:10.1109/RBME.2016.2580218
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