高原地区肺动脉血栓栓塞的临床特点及危险因素分析

曹成瑛; 陈秋红; 陈红; 王生元; 罗焕

doi:10.16016/j.1000-5404.201608028

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高原地区肺动脉血栓栓塞的临床特点及危险因素分析

临床医学 | 更新时间：2026-01-09

- 高原地区肺动脉血栓栓塞的临床特点及危险因素分析
- Clinical characteristics and risk factors of high-altitude pulmonary thromboembolism
- 第三军医大学学报 2017年39卷第4期页码：390-393
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.201608028
  中图分类号：
- 收稿：2016-08-05，
  
  纸质出版：2017-02-28
- 稿件说明：
移动端阅览
曹成瑛, 陈秋红, 陈红, 等. 高原地区肺动脉血栓栓塞的临床特点及危险因素分析[J]. 第三军医大学学报, 2017,39(4):390-393.

Chengyin Cao, Qiuhong Chen, Hong Chen, et al. Clinical characteristics and risk factors of high-altitude pulmonary thromboembolism[J]. J Third Mil Med Univ, 2017, 39(4): 390-393.
曹成瑛, 陈秋红, 陈红, 等. 高原地区肺动脉血栓栓塞的临床特点及危险因素分析[J]. 第三军医大学学报, 2017,39(4):390-393. DOI： 10.16016/j.1000-5404.201608028.

Chengyin Cao, Qiuhong Chen, Hong Chen, et al. Clinical characteristics and risk factors of high-altitude pulmonary thromboembolism[J]. J Third Mil Med Univ, 2017, 39(4): 390-393. DOI： 10.16016/j.1000-5404.201608028.

摘要

Abstract

Objective

To analyze the clinical features and related risk factors of patients with pulmonary thromboembolism(PTE) living in plateau area

for a better understanding of the incidence of high-altitude PTE.

Method

By using case-control study method

54 patients with PTE living in the altitude of 2 500~4 500 m and 36 patients with PTE living in the altitude of 1 800~2 450 m who were treated in our hospital during January 2013 and March 2016 were recruited and assigned into plateau group and control group. Clinical data of all patients were retrospectively analyzed.

Results

Among the 54 patients with PTE

40 cases (74.1%) had deep vein thrombosis (DVT)

of which 12 cases (22.2%) were concurrent high-altitude polycythemia; 9 cases (16.7%) had chronic obstructive pulmonary disease (COPD) including 3 cases(5.6%) complicated by DVT; 3 cases(5.6%) had pulmonary embolism accompanied with high-altitude polycythemia; 1 patient with coronary heart disease (1.9%) had pulmonary embolism secondary to high-altitude polycythemia; 4 cases (7.4%) occurred with other reasons. One-way analysis of variance(ANOVA) showed t

hat there were significant differences in the levels of dyspnea

chest pain

hypoxemia

pulmonary hypertension

high-altitude polycythemia

red blood cell count and hemoglobin (HGB) concentration between the plateau and control groups (

0.05 ). Multivariate non-conditional logistic regression analysis showed that the count of red blood cells and elevated HGB concentration were independent risk factors for PTE incidence in plateau areas (

=13.624

10.680).

Conclusion

PTE occurred in plateau area has its own characteristics

which is closely related to high-altitude polycythemia and elevated HGB concentration.

关键词

Keywords

references

Aujesky D Jiménez D Mor M K Weekend versus weekday admission and mortality after acute pulmonary embolism. Circulation 2009 119 7 962 968 10.1161/CIRCULATIONAHA.108.824292 Aujesky D, Jiménez D, Mor M K, et al. Weekend versus weekday admission and mortality after acute pulmonary embolism. Circulation[J]. 2009, 119(7): 962-968. DOI: 10.1161/CIRCULATIONAHA.108.824292

Anand A C Jha S K Saha A Thrombosis as a complication of extended stay at high altitude Natl Med J India 2001 14 4 197 201 http://www.researchgate.net/publication/11798971_Thrombosis_as_a_complication_of_extended_stay_at_high_altitude Anand A C, Jha S K, Saha A, et al. Thrombosis as a complication of extended stay at high altitude[J]. Natl Med J India, 2001 , 14(4): 197-201.

陈泉芳邹小英陈一强 2009-2013年某医院肺栓塞住院患者的变化趋势及其危险因素构成比分析现代预防医学 2016 43 2 376 378 http://www.cnki.com.cn/Article/CJFDTOTAL-XDYF201602054.htm 陈泉芳, 邹小英, 陈一强, 等. 2009-2013年某医院肺栓塞住院患者的变化趋势及其危险因素构成比分析[J]. 现代预防医学, 2016, 43(2): 376-378, 381.

中华医学会呼吸病学分会肺血栓栓塞症的诊断与治疗指南(草案) 中华结核和呼吸杂志 2001 24 5 259 267 10.3760/j:issn:1001-0939 中华医学会呼吸病学分会. 肺血栓栓塞症的诊断与治疗指南(草案)[J]. 中华结核和呼吸杂志, 2001, 24(5): 259-267. DOI: 10.3760/j: issn: 1001-0939

中华医学会高原医学分会关于统一使用慢性高原(山)病“青海标准"的决定高原医学杂志 2007 17 1 1 2 10.3969/j.issn.1007-3809.2007.01.001 中华医学会高原医学分会. 关于统一使用慢性高原(山)病“青海标准"的决定[J]. 高原医学杂志, 2007, 17(1): 1-2. DOI: 10.3969/j.issn.1007-3809.2007.01.001

中华人民共和国卫生部慢性阻塞性肺疾病诊断标准国际呼吸杂志 2011 31 1 1 2 10.3760/cma.j.issn.1673-436X.2011.01.001 中华人民共和国卫生部.慢性阻塞性肺疾病诊断标准[J].国际呼吸杂志, 2011, 31(1): 1-2. DOI: 10.3760/cma.j.issn.1673-436X.2011.01.001

王占刚李海玲李瑛高原地区慢性肺心病特点及呼吸衰竭诊断标准探讨高原医学杂志 1996 6 1 13 17 王占刚, 李海玲, 李瑛. 高原地区慢性肺心病特点及呼吸衰竭诊断标准探讨[J]. 高原医学杂志, 1996, 6(1): 13-17.

刘晓婷林光柱赵学忠 303例住院肺栓塞患者危险因素分析中华流行病学杂志 2011 32 12 1275 1277 10.3760/cma.j.issn.0254-6450.2011.12.021 刘晓婷, 林光柱, 赵学忠, 等. 303例住院肺栓塞患者危险因素分析[J]. 中华流行病学杂志, 2011, 32(12): 1275-1277.DOI: 10.3760/cma.j.issn.0254-6450.2011.12.021

中华医学会心血管病学分会肺血管病学组急性肺血栓栓塞症诊断治疗中国专家共识中华内科杂志 2010 49 1 74 81 10.3760/cma.j.issn.0578-1426 中华医学会心血管病学分会肺血管病学组.急性肺血栓栓塞症诊断治疗中国专家共识[J]. 中华内科杂志, 2010, 49(1): 74-81. DOI: 10.3760/cma.j.issn.0578-1426

吴天一我国青藏高原慢性高原病研究的最新进展中国实用内科杂志 2012 32 5 321 323 http://www.cnki.com.cn/Article/CJFDTOTAL-SYNK201205002.htm 吴天一. 我国青藏高原慢性高原病研究的最新进展[J]. 中国实用内科杂志, 2012, 32(5): 321-323.

Kumar D R Hanlin E Glurich I Virchow's contribution to the understanding of thrombosis and cellular biology Clin Med Res 2010 8 3-4 168 172 10.3121/cmr.2009.866 Kumar D R, Hanlin E, Glurich I, et al. Virchow's contribution to the understanding of thrombosis and cellular biology[J]. Clin Med Res, 2010, 8(3-4): 168-172. DOI: 10.3121/cmr.2009.866

León-Velarde F Maggiorini M Reeves J T Consensus statement on chronic and subacute high altitude diseases High Alt Med Biol 2005 6 2 147 157 10.1089/ham.2005.6.147 León-Velarde F, Maggiorini M, Reeves J T, et al. Consensus statement on chronic and subacute high altitude diseases[J]. High Alt Med Biol, 2005, 6(2): 147-157. DOI: 10.1089/ham.2005.6.147

徐英江金毕杨超 459例肺栓塞临床特点分析中华普通外科杂志 2015 30 12 979 982 10.3760/cma.j.issn.1007-631X 徐英江, 金毕, 杨超, 等. 459例肺栓塞临床特点分析[J]. 中华普通外科杂志, 2015, 30(12): 979-982. DOI: 10.3760/cma.j.issn.1007-631X

张理昝文明李国杰高原红细胞增多症合并深静脉血栓的临床观察高原医学杂志 2006 16 3 34 36 10.3969/j.issn.1007-3809 张理, 昝文明, 李国杰. 高原红细胞增多症合并深静脉血栓的临床观察[J]. 高原医学杂志, 2006, 16(3): 34-36. DOI: 10.3969/j.issn.1007-3809

Gupta N Ashraf M Z Exposure to high altitude: a risk factor for venous thromboembolism Semin Thromb Hemost 2012 38 2 156 163 10.1055/s-0032-1301413 Gupta N, Ashraf M Z. Exposure to high altitude: a risk factor for venous thromboembolism[J]. Semin Thromb Hemost, 2012, 38(2): 156-163. DOI: 10.1055/s-0032-1301413

Jiang C Chen J Liu F Chronic mountain sickness in Chinese Han males who migrated to the Qinghai-Tibetan plateau: application and evaluation of diagnostic criteria for chronic mountain sickness BMC Public Health 2014 14 1 1 11 10.1186/1471-2458-14-701 Jiang C, Chen J, Liu F, et al. Chronic mountain sickness in Chinese Han males who migrated to the Qinghai-Tibetan plateau: application and evaluation of diagnostic criteria for chronic mountain sickness[J]. BMC Public Health, 2014, 14(1): 1-11.DOI: 10.1186/1471-2458-14-701

陈秋红路霖祁国荣高原地区先天性心脏病并发肺动脉高压的调查分析中华医学杂志 2011 91 44 3120 3122 10.3760/cma.j.issn.0376-2491 陈秋红, 路霖, 祁国荣, 等. 高原地区先天性心脏病并发肺动脉高压的调查分析[J]. 中华医学杂志, 2011, 91(44): 3120-3122. DOI: 10.3760/cma.j.issn.0376-2491

边惠萍高原红细胞增多并发肺动脉栓塞的临床分析高原医学杂志 2008 18 3 19 20 10.3969/j.issn.1007-3809 边惠萍.高原红细胞增多并发肺动脉栓塞的临床分析[J].高原医学杂志, 2008, 18(3): 19-20. DOI: 10.3969/j.issn.1007-3809

Konstantinides S V Torbicki A Agnelli G Corrigendum to: 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism Eur Heart J 2015 36 39 2642 10.1093/eurheartj/ehu479 Konstantinides S V, Torbicki A, Agnelli G, et al. Corrigendum to: 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism[J]. Eur Heart J, 2015, 36(39): 2642. DOI: 10.1093/eurheartj/ehu479

高芬杜发茂拉周青海高原慢性阻塞性肺疾病所致慢性肺源性心脏病流行病学调查国际呼吸杂志 2011 31 13 989 992 10.3760/cma.j.issn.1673-436X 高芬, 杜发茂, 拉周, 等.青海高原慢性阻塞性肺疾病所致慢性肺源性心脏病流行病学调查[J]. 国际呼吸杂志, 2011, 31(13): 989-992.DOI: 10.3760/cma.j.issn.1673-436X

关巍格日力高原环境对呼吸系统疾病的影响中华医学杂志 2015 95 30 2491 2493 10.3760/cma.j.issn.0376-2491 关巍, 格日力.高原环境对呼吸系统疾病的影响[J]. 中华医学杂志, 2015, 95(30): 2491-2493. DOI: 10.3760/cma.j.issn.0376-2491

Güvenç T S Kul S Dogan C Assessment of right ventricular geometry and mechanics in chronic obstructive pulmonary disease patients living at high altitude Int J Cardiovasc Imaging 2014 30 7 1305 1313 10.1007/s10554-014-0475-z Güvenç T S, Kul S, Dogan C, et al. Assessment of right ventricular geometry and mechanics in chronic obstructive pulmonary disease patients living at high altitude[J]. Int J Cardiovasc Imaging, 2014, 30(7): 1305-1313. DOI: 10.1007/s10554-014-0475-z

Ristić L Rancić M Pejcić T Pulmonary embolism in patientswith chronic hypoxemia Med Pregl 2010 63 7-8 492 496 10.2298/mpns1008492r Ristić L, Rancić M, Pejcić T. Pulmonary embolism in patientswith chronic hypoxemia[J].Med Pregl, 2010, 63(7-8): 492-496. DOI: 10.2298/mpns1008492r

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