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1.重庆医科大学附属大学城医院精神科,重庆 401331
2.重庆医科大学附属第一医院胃肠外科,重庆 400000
3.重庆医科大学附属第一医院精神科,重庆 400000
李静然,Email:ljr12167027@163.com,研究方向:抑郁障碍。
王 我,Email:wangwo@cqmu.edu.cn。
收稿:2026-01-24,
修回:2026-03-19,
录用:2026-03-20,
纸质出版:2026-05-28
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李静然,龚发平,曾梦华,等.心理与行为因素促进短期减重效果的显变量路径与中介分析[J].重庆医科大学学报,2026,51(5):703-708.
Li Jingran,Gong Faping,Zeng Menghua,et al.An observed variable path and mediation analysis of psychological and behavioral factors promoting short-term weight loss outcomes[J].Journal of Chongqing Medical University,2026,51(5):703-708.
李静然,龚发平,曾梦华,等.心理与行为因素促进短期减重效果的显变量路径与中介分析[J].重庆医科大学学报,2026,51(5):703-708. DOI: 10.13406/j.cnki.cyxb.004094.
Li Jingran,Gong Faping,Zeng Menghua,et al.An observed variable path and mediation analysis of psychological and behavioral factors promoting short-term weight loss outcomes[J].Journal of Chongqing Medical University,2026,51(5):703-708. DOI: 10.13406/j.cnki.cyxb.004094.
目的
2
探讨腹腔镜袖状胃切除术(laparoscopic sleeve gastrectomy,LSG)后患者抑郁与睡眠质量的改善,以及是否通过减少暴食行为影响短期减重效果。
方法
2
对133例接受LSG的肥胖患者进行术前及术后3个月随访,评估抑郁(patient health questionnaire-9,PHQ-9)、焦虑(generalized anxiety disorder-7,GAD-7)、睡眠质量(pittsburgh sleep quality index,PSQI)、暴食行为(binge eating scale,BES)及体质量指标,以百分比总减重(percentage of total weight loss,%TWL)为主要结局。采用配对样本
t
检验比较术前术后差异,独立样本检验比较减重达标组(%TWL≥20%)与未达标组的改善幅度,并基于Δ分数构建显变量路径与中介模型(饱和模型),分析各变量之间的关系。
结果
2
术后3个月,患者抑郁、焦虑、睡眠质量及暴食行为均明显改善(
P
<
0.01)。减重达标组在抑郁、睡眠及暴食行为的改善幅度上均优于未达标组(
P
<
0.01)。路径分析显示,抑郁与睡眠改善能直接预测%TWL,也通过促进暴食行为改善间接影响%TWL。中介分析表明,暴食行为改善在抑郁、睡眠改善与%TWL之间起到部分中介作用。
结论
2
LSG术后心理与行为因素的改善与短期减重效果相关,暴食行为的改善是抑郁和睡眠改善影响减重结局的中介路径。
Objective
2
To investigate the improvements in depression and sleep quality after laparoscopic sleeve gastrectomy(LSG) and whether such improvements promotes short-term weight loss by reducing binge eating behavior.
Methods
2
A total of 133 obese patients who underwent LSG were assessed before surgery and were followed up for 3 months after surgery. Related indicators were evaluated,including depression(Patient Health Questionnaire-9),anxiety(Generalized Anxiety Disorder-7),sleep qua
lity (Pittsburgh Sleep Quality Index),binge eating behavior(Binge Eating Scale),and body weight,with percentage of total weight loss(%TWL) as the primary outcome measure. The paired samples
t
-test was used for comparison before and after surgery,and the independent samples
t
-test was used to compare the degree of improvement between the weight loss achievement group(%TWL≥20%) and the non-achievement group. An observed variable path and mediation model(saturated model) based on change scores was constructed to examine the association between variables.
Results
2
At 3 months after surgery,the patients showed significant improvements in depression,anxiety,sleep quality,and binge eating behavior(
P
<
0.01). Compared with the non-achievement group,the weight loss achievement group had significantly greater improvements in depression,sleep quality,and binge eating behavior(
P
<
0.01). The path analysis showed that improvement in depression and sleep quality could not only directly predict %TWL but also indirectly affect %TWL by promoting the improvement in binge eating behavior. The mediation analysis showed that the improvement in binge eating behavior played a partial mediating role in the association between the improvement in depression,sleep quality and %TWL.
Conclusion
2
The improvement in psychological and behavioral factors after LSG is associated with short-term weight loss outcomes,and the improvement in binge eating behavior is a mediating pathway through which the improvements in depression and sleep quality affect weight loss outcomes.
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