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昆明医科大学第一附属医院国际医学部,昆明 650000
陈 睿,Email:982971468@qq.com,研究方向:糖尿病及其并发症。
韩 睿,Email:tnb5324888@yeah.net。
收稿:2022-11-08,
修回:2024-04-13,
录用:2024-05-10,
纸质出版:2025-01-28
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陈睿,朱文卓,吴于滨,等.云南晋宁区彝族聚集地2型糖尿病患病率与影响因素分析[J].重庆医科大学学报,2025,50(1):72-79.
Chen Rui,Zhu Wenzhuo,Wu Yubin,et al.Prevalence rate of type 2 diabetes mellitus and related influencing factors in the Yi population in Jinning District,Yunnan Province,China[J].Journal of Chongqing Medical University,2025,50(1):72-79.
陈睿,朱文卓,吴于滨,等.云南晋宁区彝族聚集地2型糖尿病患病率与影响因素分析[J].重庆医科大学学报,2025,50(1):72-79. DOI: 10.13406/j.cnki.cyxb.003697.
Chen Rui,Zhu Wenzhuo,Wu Yubin,et al.Prevalence rate of type 2 diabetes mellitus and related influencing factors in the Yi population in Jinning District,Yunnan Province,China[J].Journal of Chongqing Medical University,2025,50(1):72-79. DOI: 10.13406/j.cnki.cyxb.003697.
目的
2
了解云南晋宁区彝族聚集地人群糖尿病患病率,并进行影响因素分析,为该地区彝族糖尿病的防治提供依据。
方法
2
采用方便抽样法对云南省昆明市晋宁区彝族、汉族共488例人群进行现况调查。对所有研究人群进行现场问卷调查,完善相关体格指标及生化指标,采用ELISA法检测人真胰岛素(true insulin,TI)、人胰岛素原(human proinsulin,PI)、维生素D受体(vitamin D receptor,VDR)血清水平。
结果
2
云南昆明市晋宁区彝族2型糖尿病(type 2 diabetes mellitus,T2DM)总患病率为11.11%(标化率5.7%),汉族T2DM总患病率为7.53%(标化率4.98%)。Logistic回归显示,高的胱抑素C(cystatin C,CysC)、VDR水平是彝族人群T2DM的危险因素,超重、肥胖、高的尿酸(uric acid,UA)、VDR水平是汉族人群T2DM的危险因素。
结论
2
云南昆明市晋宁区彝族T2DM患病率高于汉族,彝族、汉族间T2DM的独立危险因素存在统计学差异,针对不同人群采取个体化的T2DM防治措施是有必要的。
Objective
2
To investigate the prevalence rate of diabetes and related influencing factors in the Yi population in Jinning District,Yunnan Province,China,and to provide a basis for the prevention and treatment of diabetes in the Yi population.
Methods
2
The convenience sampling method was used to conduct a prevalence survey among 488 individuals in the Yi and Han populations in Jinning District,Kunming City,Yunnan Province. An on-site questionnaire survey was conducted among the study population,and all individuals received physical examination and measurement of biochemical parameters. ELISA was used to measure the serum levels of true insulin(TI),human proinsulin(PI),and vitamin D receptor(VDR).
Results
2
The overall prevalence rate of type 2 diabetes mellitus(T2DM) was 11.11%(standardized rate 5.7%) in the Yi population in Jinning District,and the overall prevalence rate of T2DM was 7.53%(standardized rate 4.98%) in the Han population. The logistic regression analysis showed that high levels of cystatin C(CysC) and VDR were risk factors for T2DM in the Yi population,and overweight,obesity,and high levels of uric acid and VDR were risk factors for T2DM in the Han population.
Conclusion
2
The prevalence rate of T2DM in the Yi population in Jinning District is higher than that in the Han population,and there are differences in the independent risk factors for T2DM between the Yi and Han populations. It is necessary to adopt individualized T2DM prevention and control measures for different populations.
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