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重庆医科大学附属第一医院神经内科,重庆 400016
胥小诺,Email:xxn_hand@163.com,研究方向:头痛、眩晕机制及诊疗。
周冀英,Email:zheadache@163.com。
收稿:2024-01-30,
修回:2024-02-29,
录用:2024-03-04,
纸质出版:2024-05-28
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胥小诺,董亮,周冀英.偏头痛急性治疗药物新进展及优化策略[J].重庆医科大学学报,2024,49(5):577-582.
Xu Xiaonuo,Dong Liang,Zhou Jiying.Medications for the acute treatment of migraine: new advances and optimization strategies[J].Journal of Chongqing Medical University,2024,49(5):577-582.
胥小诺,董亮,周冀英.偏头痛急性治疗药物新进展及优化策略[J].重庆医科大学学报,2024,49(5):577-582. DOI: 10.13406/j.cnki.cyxb.003491.
Xu Xiaonuo,Dong Liang,Zhou Jiying.Medications for the acute treatment of migraine: new advances and optimization strategies[J].Journal of Chongqing Medical University,2024,49(5):577-582. DOI: 10.13406/j.cnki.cyxb.003491.
偏头痛患者的急性治疗旨在快速缓解头痛和伴随症状,是偏头痛防治主要的手段之一。近年来偏头痛急性治疗药物取得了一些新进展,目的是提高治疗的有效性和安全性。过度使用急性治疗药物和急性治疗效果不佳是偏头痛慢性化的重要危险因素。不同的急性治疗药物对偏头痛慢性化的影响可能不同。偏头痛的急性治疗仍有很大的优化空间,临床医生应根据患者自身情况制定个体化治疗方案,提高急性治疗效果,预防偏头痛慢性化。本文对偏头痛急性治疗的现状、策略以及急性治疗与偏头痛慢性化之间的关系进行综述。
The acute treatment of migraine aims to provide rapid relief of headache and accompanying symptoms and is one of the main methods for the prevention and treatment of migraine. In recent years,new advances have been made in medications for the acute treatment of migraine,with the aim to improve the efficacy and safety of treatment. Excessive use of acute treatment medications and ineffective acute treatment are important risk factors for the chronicity of migraine. Different acute treatment medications may have different effects on the chronicity of migraine. There is still much room for the optimization of migraine acute treatment,and clinicians should develop individualized treatment regimens based on the specific conditions of the patient,so as to improve the efficacy of acute treatment and prevent the chronicity of migraine.This article reviews the current situation and strategies of acute treatment of migraine and the relationship between acute treatment and chronic migraine.
Headache Classification Committee of the International Headache Society(IHS) . The International Classification of Headache Disorders,3rd edition [J ] . Cephalalgia , 2018 , 38 ( 1 ): 1 - 211 .
Ashina M , Katsarava Z , Do TP , et al . Migraine:epidemiology and systems of care [J ] . Lancet , 2021 , 397 ( 10283 ): 1485 - 1495 .
Natoli JL , Manack A , Dean B , et al . Global prevalence of chronic migraine:a systematic review [J ] . Cephalalgia , 2010 , 30 ( 5 ): 599 - 609 .
Hovaguimian A , Roth J . Management of chronic migraine [J ] . BMJ , 2022 , 379 : e067670 .
Lipton RB , Buse DC , Nahas SJ , et al . Risk factors for migraine disease progression:a narrative review for a patient-centered approach [J ] . J Neurol , 2023 , 270 ( 12 ): 5692 - 5710 .
Diener HC , Tassorelli C , Dodick DW , et al . Guidelines of the International Headache Society for controlled trials of acute treatment of migraine attacks in adults:fourth edition [J ] . Cephalalgia , 2019 , 39 ( 6 ): 687 - 710 .
Sacco S , Lampl C , Amin FM , et al . European Headache Federation(EHF) consensus on the definition of effective treatment of a migraine attack and of triptan failure [J ] . J Headache Pain , 2022 , 23 ( 1 ): 133 .
Ashina M , Buse DC , Ashina H , et al . Migraine:integrated approaches to clinical management and emerging treatments [J ] . Lancet , 2021 , 397 ( 10283 ): 1505 - 1518 .
Eigenbrodt AK , Ashina H , Khan S , et al . Diagnosis and management of migraine in ten steps [J ] . Nat Rev Neurol , 2021 , 17 ( 8 ): 501 - 514 .
Lipton RB , Kolodner K , Bigal ME , et al . Validity and reliability of the Migraine-Treatment Optimization Questionnaire [J ] . Cephalalgia , 2009 , 29 ( 7 ): 751 - 759 .
Bigal ME , Borucho S , Serrano D , et al . The acute treatment of episodic and chronic migraine in the USA [J ] . Cephalalgia , 2009 , 29 ( 8 ): 891 - 897 .
Serrano D , Buse DC , Manack Adams A , et al . Acute treatment optimization in episodic and chronic migraine:results of the American Migraine Prevalence and Prevention(AMPP) Study [J ] . Headache , 2015 , 55 ( 4 ): 502 - 518 .
Takeshima T , Ueda K , Komori M , et al . Potential unmet needs in acute treatment of migraine in Japan:results of the Overcome(Japan) study [J ] . Adv Ther , 2022 , 39 ( 11 ): 5176 - 5190 .
Marmura MJ , Silberstein SD , Schwedt TJ . The acute treatment of migraine in adults:the American headache society evidence assessment of migraine pharmacotherapies [J ] . Headache , 2015 , 55 ( 1 ): 3 - 20 .
中国医师协会神经内科医师分会 , 中国研究型医院学会头痛与感觉障碍专业委员会 . 中国偏头痛诊治指南(2022版) [J ] . 中国疼痛医学杂志 , 2022 , 28 ( 12 ): 881 - 898 .
The Chinese Physician Association neurologist branch , Chinese Society of Research Hospital Headache and Sensory Disorders Special Committee . Guidelines for diagnosis and treatment of migraine in China_2022 edition) [J ] . Chin J Pain Med , 2022 , 28 ( 12 ): 881 - 898 .
Amundsen S , Nordeng H , Nezvalová-Henriksen K , et al . Pharmacological treatment of migraine during pregnancy and breastfeeding [J ] . Nat Rev Neurol , 2015 , 11 ( 4 ): 209 - 219 .
Bigal ME , Lipton RB . Excessive opioid use and the development of chronic migraine [J ] . Pain , 2009 , 142 ( 3 ): 179 - 182 .
Villalón CM , VanDenBrink AM . The role of 5-hydroxytryptamine in the pathophysiology of migraine and its relevance to the design of novel treatments [J ] . Mini Rev Med Chem , 2017 , 17 ( 11 ): 928 - 938 .
Ong JJY , de Felice M . Migraine treatment:current acute medications and their potential mechanisms of action [J ] . Neurotherapeutics , 2018 , 15 ( 2 ): 274 - 290 .
de Vries T , Villalón CM , MaassenVanDenBrink A . Pharmacological treatment of migraine:CGRP and 5-HT beyond the triptans [J ] . Pharmacol Ther , 2020 , 211 : 107528 .
Ferrari MD , Goadsby PJ , Burstein R , et al . Migraine [J ] . Nat Rev Dis Primers , 2022 , 8 : 2 .
Dodick D , Lipton RB , Martin V , et al . Consensus statement:cardiovascular safety profile of triptans(5-HT agonists) in the acute treatment of migraine [J ] . Headache , 2004 , 44 ( 5 ): 414 - 425 .
Wammes-van der Heijden EA , Rahimtoola H , Leufkens HG , et al . Risk of ischemic complications related to the intensity of triptan and ergotamine use [J ] . Neurology , 2006 , 67 ( 7 ): 1128 - 1134 .
Roberto G , Piccinni C , D’Alessandro R , et al . Triptans and serious adverse vascular events:data mining of the FDA Adverse Event Reporting System database [J ] . Cephalalgia , 2014 , 34 ( 1 ): 5 - 13 .
Diener HC . The risks or lack thereof of migraine treatments in vascular disease [J ] . Headache , 2020 , 60 ( 3 ): 649 - 653 .
Olesen J , Diener HC , Schoenen J , et al . No effect of eletriptan administration during the aura phase of migraine [J ] . Eur J Neurol , 2004 , 11 ( 10 ): 671 - 677 .
Steiner TJ , Jensen R , Katsarava Z , et al . Aids to management of headache disorders in primary care(2nd edition) [J ] . J Headache Pain , 2019 , 20 ( 1 ): 57 .
Markowitz S , Saito K , Moskowitz MA . Neurogenically mediated plasma extravasation in dura mater:effect of ergot alkaloids. A possible mechanism of action in vascular headache [J ] . Cephalalgia , 1988 , 8 ( 2 ): 83 - 91 .
Tfelt-Hansen PC , Koehler PJ . History of the use of ergotamine and dihydroergotamine in migraine from 1906 and onward [J ] . Cephalalgia , 2008 , 28 ( 8 ): 877 - 886 .
Krege JH , Lipton RB , Baygani SK , et al . Lasmiditan for patients with migraine and contraindications to triptans:a post hoc analysis [J ] . Pain Ther , 2022 , 11 ( 2 ): 701 - 712 .
Croop R , Goadsby PJ , Stock DA , et al . Efficacy,safety,and tolerability of rimegepant orally disintegrating tablet for the acute treatment of migraine:a randomised,phase 3,double-blind,placebo-controlled trial [J ] . Lancet , 2019 , 394 ( 10200 ): 737 - 745 .
Dodick DW , Lipton RB , Ailani J , et al . Ubrogepant for the treatment of migraine [J ] . N Engl J Med , 2019 , 381 ( 23 ): 2230 - 2241 .
Lipton RB , Croop R , Stock EG , et al . Rimegepant,an oral calcitonin gene-related peptide receptor antagonist,for migraine [J ] . N Engl J Med , 2019 , 381 ( 2 ): 142 - 149 .
Lipton RB , Dodick DW , Ailani J , et al . Effect of ubrogepant vs placebo on pain and the most bothersome associated symptom in the acute treatment of migraine:the ACHIEVE Ⅱ randomized clinical trial [J ] . JAMA , 2019 , 322 ( 19 ): 1887 - 1898 .
Blumenfeld AM , Goadsby PJ , Dodick DW , et al . Efficacy of ubrogepant based on prior exposure and response to triptans:a post hoc analysis [J ] . Headache , 2021 , 61 ( 3 ): 422 - 429 .
Lipton RB , Blumenfeld A , Jensen CM , et al . Efficacy of rimegepant for the acute treatment of migraine based on triptan treatment experience:Pooled results from three phase 3 randomized clinical trials [J ] . Cephalalgia , 2023 , 43 ( 2 ): 3331024221141686 .
Yang LPH . Sumatriptan/naproxen sodium:a review of its use in adult patients with migraine [J ] . Drugs , 2013 , 73 ( 12 ): 1339 - 1355 .
Syed YY . Sumatriptan/naproxen sodium:a review in migraine [J ] . Drugs , 2016 , 76 ( 1 ): 111 - 121 .
Brandes JL , Kudrow D , Stark SR , et al . Sumatriptan-naproxen for acute treatment of migraine:a randomized trial [J ] . JAMA , 2007 , 297 ( 13 ): 1443 - 1454 .
Mathew NT , Landy S , Stark S , et al . Fixed-dose sumatriptan and naproxen in poor responders to triptans with a short half-life [J ] . Headache , 2009 , 49 ( 7 ): 971 - 982 .
Buse DC , Greisman JD , Baigi K , et al . Migraine progression:a systematic review [J ] . Headache , 2019 , 59 ( 3 ): 306 - 338 .
Xu JJ , Kong FY , Buse DC . Predictors of episodic migraine transformation to chronic migraine:a systematic review and meta-analysis of observational cohort studies [J ] . Cephalalgia , 2020 , 40 ( 5 ): 503 - 516 .
Katsarava Z , Schneeweiss S , Kurth T , et al . Incidence and predictors for chronicity of headache in patients with episodic migraine [J ] . Neurology , 2004 , 62 ( 5 ): 788 - 790 .
Schwedt TJ , Alam A , Reed ML , et al . Factors associated with acute medication overuse in people with migraine:results from the 2017 migraine in America symptoms and treatment(MAST) study [J ] . J Headache Pain , 2018 , 19 ( 1 ): 38 .
Lipton RB , Fanning KM , Serrano D , et al . Ineffective acute treatment of episodic migraine is associated with new-onset chronic migraine [J ] . Neurology , 2015 , 84 ( 7 ): 688 - 695 .
Bigal ME , Serrano D , Buse D , et al . Acute migraine medications and evolution from episodic to chronic migraine:a longitudinal population-based study [J ] . Headache , 2008 , 48 ( 8 ): 1157 - 1168 .
Lipton RB , Serrano D , Nicholson RA , et al . Impact of NSAID and Triptan use on developing chronic migraine:results from the American migraine prevalence and prevention(AMPP) study [J ] . Headache , 2013 , 53 ( 10 ): 1548 - 1563 .
Scher AI , Lipton RB , Stewart WF , et al . Patterns of medication use by chronic and episodic headache sufferers in the general population:results from the frequent headache epidemiology study [J ] . Cephalalgia , 2010 , 30 ( 3 ): 321 - 328 .
Bigal ME , Lipton RB . Excessive acute migraine medication use and migraine progression [J ] . Neurology , 2008 , 71 ( 22 ): 1821 - 1828 .
Barreto T . Acute treatments for episodic migraine in adults [J ] . Am Fam Physician , 2021 , 104 ( 5 ): 509 - 512 .
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