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1.重庆医科大学附属儿童医院,门诊部
2.重庆医科大学附属儿童医院,护理部
3.血液科;国家儿童健康与疾病临床医学研究中心; 儿童发育疾病研究教育部重点实验室;儿童神经发育与认知障碍重庆市重点实验室,重庆 400014
沈雨晴,Email:1785981643@qq.com,研究方向:血液肿瘤儿童的适应行为问题。
莫 霖,Email:molin999@126.com。
收稿:2023-10-01,
修回:2024-01-22,
录用:2024-02-26,
纸质出版:2024-03-28
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沈雨晴,莫霖,余璐,等.急性白血病患儿行为特征的潜在类别分析及影响因素[J].重庆医科大学学报,2024,49(3):303-310.
Shen Yuqing,Mo Lin,Yu Lu,et al.Latent class analysis of behavioral characteristics of children with acute leukemia and associated influencing factors[J].Journal of Chongqing Medical University,2024,49(3):303-310.
沈雨晴,莫霖,余璐,等.急性白血病患儿行为特征的潜在类别分析及影响因素[J].重庆医科大学学报,2024,49(3):303-310. DOI: 10.13406/j.cnki.cyxb.003445.
Shen Yuqing,Mo Lin,Yu Lu,et al.Latent class analysis of behavioral characteristics of children with acute leukemia and associated influencing factors[J].Journal of Chongqing Medical University,2024,49(3):303-310. DOI: 10.13406/j.cnki.cyxb.003445.
目的
2
利用潜在类别分析法探讨急性白血病患儿行为特征的潜在类别及影响因素,为制定白血病患儿行为问题精准干预策略提出循证依据。
方法
2
便利抽样法选取重庆医科大学附属儿童医院血液科202例急性白血病患儿及其照顾者为研究对象,使用一般资料调查表、Rutter 儿童行为问卷、一般家庭功能分量表、社会支持评定量表对其进行调查。利用潜在类别分析对急性白血病患儿行为特征进行分类,采用无序多分类logistic回归分析各因素对不同类别的影响。
结果
2
急性白血病患儿行为特征可分为3种类型,其中冲动-不友善型占50%,情绪-躯体障碍型占33.66%,良好行为型占16.34%;无序多分类logistic回归结果显示,不健康的家庭功能、男性患儿易发展为冲动-不友善型,不健康的家庭功能、男性患儿、治疗期易发展为情绪-躯体障碍型,治疗期患儿易发展为情绪-躯体障碍型。
结论
2
急性白血病患儿行为特征存在明显不同的分类特征,与家庭功能、性别、疾病阶段关系密切。因此应针对不同类别特征的急性白血病患儿制定个性化干预措施,预防或减少其行为问题的发生,进而提升其社会适应能力及生存质量。
Objective
2
To explore the potential categories of behavioral characteristics of children with acute leukemia using latent class analysis and associated influencing factors,and to provide evidence for developing precise intervention strategies for behavioral problems in children with leukemia.
Methods
2
We selected 202 children with acute leukemia and their caregivers by convenience sampling in the Department of Hematology of Children’s Hospital of Chongqing Medical University for a survey using the General Information Questionnaire, Rutter Child Behavior Questionnaire,General Family Functioning Scale, and Social Support Rating Scale. The behavioral characteristics of children with acute leukemia were categorized using a latent class analysis, and the effects of various factors on different categories were analyzed using a multinomial logistic regression analysis.
Results
2
TThe behavioral characteristics of children with acute leukemia were classified into three types: impulsive-unfriendly type(50%),emotional-somatic disorder type (33.66%),and well-behaved type(16.34%). The multinomial logistic regression analysis showed that unhealthy family func
tioning and male were more frequently associated with the impulsive-unfriendly type compared with the well-behaved type; unhealthy family functioning,male,and being in the treatment period were more frequently associated with the emotional-somatic disorder type compared with the well-behaved type;and children in the treatment period were prone to developing the impulsive-unfriendly type compared with the emotional-somatic disorder type.
Conclusion
2
Children with acute leukemia have distinct types of behavioral features, which are closely related to family functioning, sex, and disease stage. Therefore, for different behavioral types, targeted individualized interventions should be developed to prevent or reduce the occurrence of behavioral problems in children with acute leukemia, improving their social adaptability and quality of life.
Ni X , Li Z , Li XP , et al . Socioeconomic inequalities in cancer incidence and access to health services among children and adolescents in China:a cross-sectional study [J ] . Lancet , 2022 , 400 ( 10357 ): 1020 - 1032 .
GBD Childhood Cancer Collaborators . The global burden of childhood and adolescent cancer in 2017:an analysis of the Global Burden of Disease Study 2017 [J ] . Lancet Oncol , 2019 , 20 ( 9 ): 1211 - 1225 .
Fadel SA , Boschi-Pinto C , Yu SC , et al . Trends in cause-specific mortality among children aged 5-14 years from 2005 to 2016 in India,China,Brazil,and Mexico:an analysis of nationally representative mortality studies [J ] . Lancet , 2019 , 393 ( 10176 ): 1119 - 1127 .
de Luca CR , Mulraney M , Anderson V , et al . Behavioral and emotional functioning of children and adolescents at the end of treatment for acute lymphoblastic leukemia compared to healthy peers [J ] . J Clin Psychol Med Settings , 2022 , 29 ( 2 ): 421 - 431 .
莫 霖 , 唐 艳 , 黄小燕 , 等 . 不同年龄阶段恶性肿瘤儿童行为问题及影响因素的相关研究 [J ] . 重庆医科大学学报 , 2013 , 38 ( 1 ): 105 - 108 .
Mo L , Tang Y , Huang XY , et al . Analysis on behavior problems of children with malignant tumor at various ages and their relevant influencing factors [J ] . J Chongqing Med Univ , 2013 , 38 ( 1 ): 105 - 108 .
Chiou SS , Lin PC , Liao YM , et al . A cross-sectional follow-up study of physical morbidities,neurocognitive function,and attention problems in post-treatment childhood acute lymphoblastic leukemia survivors [J ] . Kaohsiung J Med Sci , 2019 , 35 ( 6 ): 373 - 378 .
Cr V , Das G , Seth R , et al . Neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia:experience from a tertiary care center in India [J ] . Pediatr Blood Cancer , 2022 , 69 ( 6 ): e29688 .
王孟成 , 邓俏文 , 毕向阳 , 等 . 分类精确性指数Entropy在潜剖面分析中的表现:一项蒙特卡罗模拟研究 [J ] . 心理学报 , 2017 , 49 ( 11 ): 1473 - 1482 .
Wang MC , Deng QW , Bi XY , et al . Performance of the entropy as an index of classification accuracy in latent profile analysis:a Monte Carlo simulation study [J ] . Acta Psychol Sin , 2017 , 49 ( 11 ): 1473 - 1482 .
Achterhof R , Huntjens RJC , Meewisse ML , et al . Assessing the application of latent class and latent profile analysis for evaluating the construct validity of complex posttraumatic stress disorder:cautions and limitations [J ] . Eur J Psychotraumatol , 2019 , 10 ( 1 ): 1698223 .
倪 平 , 陈京立 , 刘 娜 . 护理研究中量性研究的样本量估计 [J ] . 中华护理杂志 , 2010 , 45 ( 4 ): 378 - 380 .
Ni P , Chen JL , Liu N . The sample size estimation in quantitative nursing research [J ] . Chin J Nurs , 2010 , 45 ( 4 ): 378 - 380 .
中华医学会儿科学分会血液学组,中华儿科杂志编辑委员会 . 小儿急性淋巴细胞白血病诊疗建议(第二次修订草案) [J ] . 中华儿科杂志 , 1999 , 37 ( 5 ): 305 .
Recommendations for the Diagnosis and Treatment of Pediatric Acute Lymphoblastic Leukemia (Second Revised Draft) . Chin J Pediatr , 1999 , 37 ( 5 ): 305 .
中国医师协会儿科医师分会小儿血液肿瘤专业委员会 , 中华医学会儿科学分会血液学组 . 儿童急性早幼粒细胞白血病诊疗规范(2018年版)解读 [J ] . 中华儿科杂志 , 2019 , 57 ( 10 ): 757 - 760 .
Interpretation of the Chinese guideline for diagnosis and treatment of childhood acute promyelocytic leukemia ( 2018 )[J ] . Chin J Pediatr, 2019 , 57 ( 10 ): 757 - 760 .
Rutter M . A children’s behaviour questionnaire for completion by teachers:preliminary findings [J ] . J Child Psychol Psychiatry , 1967 , 8 ( 1 ): 1 - 11 .
王玉凤 , 沈渔邨 , 顾伯美 , 等 . 北京市城区2432名学龄儿童行为问题调查报告:学校行为问题与家庭环境的关系 [J ] . 中国心理卫生杂志 , 1988 , 2 ( 3 ): 114 - 117 .
Wang YF , Shen YC , Gu BM , et al . An epidemiological study on behaviour problems in 2432 school-children in an urban area in Beijing [J ] . Chin Ment Health J , 1988 , 2 ( 3 ): 114 - 117 .
Epstein NB , Baldwin LM , Bishop DS . The McMASTER family assessment device [J ] . J Marital Fam Ther , 1983 , 9 ( 2 ): 171 - 180 .
李荣风 , 徐夫真 , 纪林芹 , 等 . 家庭功能评定量表的初步修订 [J ] . 中国健康心理学杂志 , 2013 , 21 ( 7 ): 996 - 1000 .
Li RF , Xu FZ , Ji LQ , et al . Revision of family assessment device(FAD) [J ] . China J Health Psychol , 2013 , 21 ( 7 ): 996 - 1000 .
肖水源 . 《社会支持评定量表》的理论基础与研究应用 [J ] . 临床精神医学杂志 , 1994 , 4 ( 2 ): 98 - 100 .
Xiao SY . Theoretical basis and research application of social support rating scale [J ] . J Clin Psychiatry , 1994 , 4 ( 2 ): 98 - 100 .
孙文喜 , 董成龙 , 袁 颖 , 等 . Rutter儿童行为问卷调查的中国普通学龄儿童行为问题发生率meta分析 [J ] . 中国心理卫生杂志 , 2018 , 32 ( 9 ): 744 - 752 .
Sun WX , Dong CL , Yuan Y , et al . Behavioral problems among mainland general school-age children with the Rutter Child Behavior Questionnaire in China:a meta-analysis [J ] . Chin Ment Health J , 2018 , 32 ( 9 ): 744 - 752 .
刘 霞 , 王 丽 , 王念蓉 , 等 . 学龄前儿童多动行为与运动能力研究 [J ] . 重庆医学 , 2023 , 52 ( 13 ): 1954 - 1958 .
Liu X , Wang L , Wang NR , et al . Study on hyperactive behaviors and motor ability of preschoolers [J ] . Chongqing Med , 2023 , 52 ( 13 ): 1954 - 1958 .
潘小容 , 莫 霖 , 刘倩 , 等 . 学龄前恶性肿瘤患儿意志控制在家庭环境与情绪行为间的中介效应 [J ] . 中华行为医学与脑科学杂志 , 2020 , 29 ( 7 ): 629 - 634 .
Pan XR , Mo L , Liu Q , et al . Mediating effect of children’s effortful control between home environment and emotional behavioral problems among preschool children with malignant tumors [J ] . Chin J Behav Med Brain Sci , 2020 , 29 ( 7 ): 629 - 634 .
Zahed G , Koohi F . Emotional and behavioral disorders in pediatric cancer patients [J ] . Iran J Child Neurol , 2020 , 14 ( 1 ): 113 - 121 .
de Vries MA , van Litsenburg RR , Huisman J , et al . Effect of dexamethasone on quality of life in children with acute lymphoblastic leukaemia:a prospective observational study [J ] . Health Qual Life Outcomes , 2008 , 6 : 103 .
刘 倩 , 莫 霖 , 黄先巧 , 等 . 治疗期儿童青少年恶性肿瘤患儿社会适应相关因素分析 [J ] . 中国卫生统计 , 2021 , 38 ( 3 ): 391 - 395 .
Liu Q , Mo L , Huang XQ , et al . Analysis of related factors of social adaptation of children with malignant tumor in treatment period [J ] . Chin J Health Stat , 2021 , 38 ( 3 ): 391 - 395 .
Patel P , Robinson PD , Devine KA , et al . Prevention and treatment of anticipatory chemotherapy-induced nausea and vomiting in pediatric cancer patients and hematopoietic stem cell recipients:clinical practice guideline update [J ] . Pediatr Blood Cancer , 2021 , 68 ( 5 ): e28947 .
廖 婧 , 刘 可 , 卜秀青 , 等 . 恶性肿瘤患儿化疗期间身心症状困扰的纵向研究 [J ] . 护理学杂志 , 2018 , 33 ( 9 ): 30 - 33 .
Liao J , Liu K , Bu XQ , et al . Physical and psychological symptom distress among children with malignant tumor during chemotherapy:a longitudinal study [J ] . J Nurs Sci , 2018 , 33 ( 9 ): 30 - 33 .
刘锦明 , 陈庆欣 , 陈 琪 , 等 . 孤独症儿童日常执行功能与其核心症状及注意缺陷多动症状的关联 [J ] . 中山大学学报(医学科学版) , 2023 , 44 ( 5 ): 776 - 783 .
Liu JM , Chen QX , Chen Q , et al . Association between daily executive function and core symptoms,attention deficit-hyperactivity symptoms in children with autism spectrum disorder [J ] . J Sun Yat Sen Univ Med Sci , 2023 , 44 ( 5 ): 776 - 783 .
Jacola L M , Baran J , Noll R B , et al . Adaptive functioning and academic achievement in survivors of childhood acute lymphoblastic leukemia:a report from the Children's Oncology Group [J ] . Pediatr Blood Cancer , 2021 , 68 ( 4 ): e28913 .
王素华 , 陈 杰 , 李新影 . 交往不良同伴对青少年自身问题行为的影响:性别和年龄的调节作用 [J ] . 中国临床心理学杂志 , 2013 , 21 ( 2 ): 281 - 284 .
Wang SH , Chen J , Li XY . Deviant peer affliation and problem behaviors:moderating effect of sex and age [J ] . Chin J Clin Psychol , 2013 , 21 ( 2 ): 281 - 284 .
洪彬雪 , 宋戈扬 , 刘 敏 , 等 . 初中学生家庭功能对自杀相关行为的影响:抑郁的中介作用 [J ] . 四川大学学报(医学版) , 2022 , 53 ( 5 ): 866 - 871 .
Hong BX , Song GY , Liu M , et al . Effect of family function on suicide-related behaviors of junior middle school students:the mediating effect of depression [J ] . J Sichuan Univ Med Sci , 2022 , 53 ( 5 ): 866 - 871 .
薛俊磊 , 胡利娟 , 彭 慧 , 等 . 上海市某区青春前期儿童情绪和行为问题现状及其影响因素 [J ] . 中国健康教育 , 2023 , 39 ( 9 ): 783 - 789 .
Xue JL , Hu LJ , Peng H , et al . Analysis of the current situation and influencing factors of emotional and behavioral problems of children in pre-adolescence in a district of Shanghai [J ] . Chin J Health Educ , 2023 , 39 ( 9 ): 783 - 789 .
王英杰 , 李 燕 , 吴凡 . 家庭功能与学前儿童行为问题的关系:依恋回避和社交焦虑的多重中介作用 [J ] . 心理发展与教育 , 2021 , 37 ( 1 ): 76 - 83 .
Wang YJ , Li Y , Wu F . Effects of family function on pre-schoolers' problem behaviors:the sequential mediating effects of attachment avoidance and social anxiety [J ] . Psychol Dev Educ , 2021 , 37 ( 1 ): 76 - 83 .
刘艺璇 , 莫 霖 , 蔡瑞卿 , 等 . 学龄前恶性肿瘤患儿社会适应多中心调查及影响因素分析 [J ] . 护理学杂志 , 2023 , 38 ( 1 ): 19 - 22 .
Liu YX , Mo L , Cai RQ , et al . Multicenter survey and analysis on current situation and influencing factors of social adaptation among preschool children with malignancies [J ] . J Nurs Sci , 2023 , 38 ( 1 ): 19 - 22 .
谌 静 , 任小红 , 田艳珍 . 急性白血病患儿的家庭功能现状及其影响因素 [J ] . 解放军护理杂志 , 2013 , 30 ( 16 ): 15 - 18 .
Chen J , Ren XH , Tian YZ . Status and influencing factors of family function for children with acute leukemia [J ] . Nurs J Chin People’s Liberation Army , 2013 , 30 ( 16 ): 15 - 18 .
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