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1.皖南医学院临床医学院诊断学教研室,芜湖 241002
2.皖南医学院检验学院卫生检验与检疫教研室,芜湖 241002
3.马鞍山市人民医院超声科脑卒中研究中心,马鞍山 243000
4.皖南医学院公共卫生学院预防医学教研室,芜湖 241002
江明菲,Email:1582772684@qq.com, 研究方向:慢性病流行病学。
文育锋,Email:wyf@wnmc.edu.cn。
收稿:2021-08-12,
修回:2022-04-26,
录用:2022-05-19,
纸质出版:2023-02-28
移动端阅览
江明菲,吴欢,张惠萍,等.新型营养指数与颈动脉病变的相关性[J].重庆医科大学学报,2023,48(2):205-209.
Jiang Mingfei,Wu Huan,Zhang Huiping,et al.Association of a novel nutritional index with carotid artery disease[J].Journal of Chongqing Medical University,2023,48(2):205-209.
江明菲,吴欢,张惠萍,等.新型营养指数与颈动脉病变的相关性[J].重庆医科大学学报,2023,48(2):205-209. DOI: 10.13406/j.cnki.cyxb.003051.
Jiang Mingfei,Wu Huan,Zhang Huiping,et al.Association of a novel nutritional index with carotid artery disease[J].Journal of Chongqing Medical University,2023,48(2):205-209. DOI: 10.13406/j.cnki.cyxb.003051.
目的
2
探究甘油三酯(triglycerides,TG)-总胆固醇(total cholesterol,TC)-体质量(body weight,BW)指数(TG×TC×BW index,TCBI)与颈动脉病变的相关性。
方法
2
以2016年11月至2019年10月安徽省马鞍山市某医院住院、疑似稳定性颈动脉病变、满足纳入标准的患者2 290人为研究对象。根据彩色多普勒检测结果将研究对象分为颈动脉病变组(
n
=1 352)和对照组(
n
=938)。收集所有患者的一般人口学特征、临床特征、彩色多普勒检查指标和血生化检测指标。建立回归模型分析TCBI与颈动脉病变的关系。
结果
2
颈动脉病变组的TCBI(
χ
2
=
34.018
,P
<
0.001)高于对照组;高TCBI组血脂异常(
χ
2
=
143.933
,P<
0.001)、糖尿病(
χ
2
=
29.946
,P<
0.001
)
的检出率及颈内动脉阻力指数(internal carotid artery resistance index,ICA-RI)(
t=
2.468
,P=
0.014)、三酰甘油-葡萄糖(triglyceride glucose,TyG)指数(
t=
9.160
,P
<
0.001)、内中膜厚度(intima-media thickness,IMT)≥1.0 mm(
t=
34.018
,P
<
0.001)较低TCBI组高;TCBI与血脂异常(
r
=0.510
,P
<
0.001)、ICA-RI(
r
=0.363
,P
<
0.001
)
、AIP
(r
=0.714
,P
<
0.001)呈正相关;在TCBI与颈动脉病变的关联分析中,TCBI
>
1 800是颈动脉病变的独立危险因素。
结论
2
TCBI对颈动脉病变的筛查和临床诊断具有潜在应用价值。
Objective
2
To explore the association of triglycerides(TG)total cholesterol(TC)body weight(BW)index(TG×TC×BW index,TCBI)with carotid artery disease.
Methods
2
A total of 2 290 patients with suspected stable carotid artery disease who were hospitalized in a hospital of Ma'anshan City,Anhui Province from November 2016 to October 2019 were selected as the research subjects. All of them were divided into carotid artery disease group(
n
=1 352)and control group(
n
=938)according to the results of color Doppler detection. We collected the general demographic characteristics,clinical characteristics,color Doppler examination indexes and blood biochemical detection indexes. Regression models were established to analyze the relationship between TCBI and carotid artery disease.
Results
2
The TCBI of the carotid artery disease group(
χ
2
=34.018
,P
<
0.001)was higher than that of the control group;dyslipidemia(
χ
2
=143.933
,P
<
0.001)and diabetes(
χ
2
=29.946
,P
<
0.001
)
,internal carotid artery resistance index(ICA-RI)(
t
=2.468
,P
=0.014),triglyceride glucose(TyG)index(
t
=9.160
,P
<
0.001),intima-media thickness(IMT)≥ 1.0 mm(
t
=34.018
,P
<
0.001)in the high TCBI group were higher than those of the low TCBI group. TCBI was positively correlated with dyslipidemia(
r
=0.510
,P
<
0.001),ICA-RI(
r
=0.363
,P
<
0.001
)
and atherogenic index of plasma(
r
=0.714
,P
<
0.001). In the correlation analysis,the TCBI
>
1 800 was an independent risk factor for carotid artery disease.
Conclusion
2
The TCBI has potential application value in the screening and clinical diagnosis of carotid artery disease.
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