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陆军军医大学第一附属医院血液病中心,重庆 400038
黄福麟,E-mail:hflxya@tmmu.edu.cn
收稿:2025-12-25,
网络首发:2026-07-24,
纸质出版:2026-07-25
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张佳思,谭方方,黄福麟等.阶梯式上肢运动操对血液肿瘤患者PICC术后并发症的影响[J].局解手术学杂志,2026,35(07):633-637.
ZHANG Jia-si,TAN Fang-fang,HUANG Fu-lin,et al.Effects of graded upper limb exercise on PICC‑related complications in patients with hematological malignancies[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(07):633-637.
张佳思,谭方方,黄福麟等.阶梯式上肢运动操对血液肿瘤患者PICC术后并发症的影响[J].局解手术学杂志,2026,35(07):633-637. DOI: 10.11659/jjssx.12E025125.
ZHANG Jia-si,TAN Fang-fang,HUANG Fu-lin,et al.Effects of graded upper limb exercise on PICC‑related complications in patients with hematological malignancies[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(07):633-637. DOI: 10.11659/jjssx.12E025125.
目的
2
探讨阶梯式上肢运动操对血液肿瘤患者经外周置入中心静脉导管(PICC)术后并发症的影响。
方法
2
采用回顾性队列研究方法,选取我院收治的行PICC的血液肿瘤患者314例,将2020年1月至2021年12月接受常规维护的168例患者设为常规组,将2022年1月至2023年12月接受常规维护联合阶梯式上肢运动操的146例患者设为观察组。比较2组患者PICC置入术后28 d内症状性导管相关性血栓(CRT)发生率、发生部位及临床症状。记录患者无症状性CRT的生存率及生存时间、上肢功能障碍及其他并发症发生情况。
结果
2
观察组患者术后7 d内症状性CRT发生率低于常规组,术后28 d内症状性CRT总发生率低于常规组,差异均有统计学意义(
P
<
0.05)。2组患者术后8~28 d症状性CRT发生率比较,差异均无统计学意义(
P
>
0.05)。
Kaplan
-
Meier
生存分析显示,观察组患者累计无症状性CRT生存率高于常规组(
Log
-
rank χ
²=8.357,
P
=0.004)。在CRT发生部位方面,观察组患者肱静脉症状性CRT发生率低于常规组,差异有统计学意义(
P
<
0.05);2组患者腋静脉、贵要静脉、导管内症状性CRT发生率及不同症状CRT发生率比较,差异均无统计学意义(
P
>
0.05)。观察组患者上肢功能障碍发生率低于常规组,差异有统计学意义(
P
<
0.05);2组患者导管移位/脱出、导管堵塞、穿刺部位出血发生率比较,差异无统计学意义(
P
>
0.05)。
结论
2
阶梯式上肢运动操可降低血液肿瘤患者PICC术后症状性CRT及上肢功能障碍的发生风险,且不会增加导管移位/脱出、穿刺部位出血等并发症,有助于促进置管侧肢体功能恢复。
Objective
2
To investigate the effects of graded upper limb exercise on the complications after peripherally inserted central catheter (PICC) surgery in patients with hematologic malignancies.
Methods
2
A retrospective cohort study was conducted. A total of 314 patients with hematologic malignancies who underwent PICC surgery at our hospital were selected. A total of 168 patients who received routine care from January 2020 to December 2021 were designated as the conventional group, while 146 patients who received routine care plus graded upper limb exercise from January 2022 to December 2023 were designated as the observation group. The two groups were compared in terms of the incidence, location, and clinical symptoms of symptomatic catheter related thrombosis (CRT) within 28 days after PICC surgery. In addition, the survival rate and survival time of patients with asymptomatic CRT, as well as the occurrence of upper limb dysfunction and other complications were recorded.
Results
2
The observation group had significantly lower symptomatic CRT withi
n 7 days postoperatively and overall incidences of symptomatic CRT within 28 days postoperatively than the conventional group, with statistically significant differences (
P
<
0.05). No statistically significant difference was found in the incidence of symptomatic CRT from 8 to 28 days postoperatively between the two groups (
P
>
0.05).
Kaplan
‑
Meier
survival analysis revealed a significantly higher cumulative survival rate of asymptomatic CRT in the observation group compared with the conventional group (
Log
‑
rank
χ
²=8.357,
P
=0.004). Regarding CRT location, the observation group had a lower incidence of symptomatic CRT in the brachial vein compared with the conventional group, with statistically significant difference (
P
<
0.05), whereas no significant differences were found in the incidence of symptomatic CRT in the axillary vein, basilic vein, and intracatheter, or in the incidence of CRT-associated symptoms between the two groups (
P
>
0.05). The incidence of upper limb dysfunction in the observation group was lower than that in the conventional group, with statistically significant difference (
P
<
0.05). No significant differences were found in the incidences of catheter migration/dislodgement, catheter occlusion, or puncture site bleeding between the two groups (
P
>
0.05).
Conclusion
2
Graded upper limb exercise reduces the risk of symptomatic CRT and upper limb dysfunction after PICC surgery in patients with hematologic malignancies,without increasing complications such as catheter migration/dislodgement or puncture site bleeding,and contributes to the recovery of limb function on the catheterized side.
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