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1.孝感市中心医院/武汉科技大学附属孝感医院麻醉科,湖北 孝感 432000
2.孝感市中心医院/武汉科技大学附属孝感医院胸心外科,湖北 孝感 432000
收稿:2025-11-07,
纸质出版:2026-06-25
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刘宏强,程蕾,郑威.超声引导下前锯肌平面二次阻滞对胸腔镜下肺部分切除术后镇痛的影响[J].局解手术学杂志,2026,35(06):474-477.
LIU Hong-qiang,CHENG Lei,ZHENG Wei.Effect of ultrasound-guided second serratus anterior plane block on postoperative analgesia after thoracoscopic partial lung resection[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(06):474-477.
刘宏强,程蕾,郑威.超声引导下前锯肌平面二次阻滞对胸腔镜下肺部分切除术后镇痛的影响[J].局解手术学杂志,2026,35(06):474-477. DOI: 10.11659/jjssx.11E025044.
LIU Hong-qiang,CHENG Lei,ZHENG Wei.Effect of ultrasound-guided second serratus anterior plane block on postoperative analgesia after thoracoscopic partial lung resection[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(06):474-477. DOI: 10.11659/jjssx.11E025044.
目的
2
探讨超声引导下前锯肌平面二次阻滞对胸腔镜手术患者术后镇痛效果、恢复质量及炎症反应的影响。
方法
2
选取2022年8月至2023年6月在孝感市中心医院择期行胸腔镜手术的86例患者,采用随机数字表法分为前锯肌平面阻滞(SAPB)组(
n
=43)与对照组(
n
=43)。2组患者术中均接受首次超声引导下SAPB;术后24 h,SAPB组患者在超声引导下接受前锯肌平面二次阻滞,对照组患者则在相同位置注射等量生理盐水。比较2组患者术前24 h及术后48 h、72 h的生活质量恢复问卷(QoR-40)评分,术后24 h、48 h、72 h的疼痛数字评定量表(NRS)评分,术后48 h内舒芬太尼用量,术后24 h、48 h、72 h的血清白细胞介素-6(IL-6)与白细胞介素-10(IL-10)水平,以及术后并发症和不良反应发生率。
结果
2
对重复测量数据进行方差分析表明,QoR-40评分在组别、时间及交互作用上均具有统计学意义(
P
<
0.05)。事后检验发现,SAPB组患者术后48 h、72 h的QoR-40评分均显著高于对照组(
P
<
0.05)。在疼痛控制方面,NRS评分在组别、时间及交互作用上均具有统计学意义(
P
<
0.001),SAPB组患者术后48 h的NRS评分及舒芬太尼用量均显著低/少于对照组(
P
<
0.05)。在炎症反应方面,SAPB组患者术后48 h、72 h的IL-6水平显著低于对照组(
P
<
0.01),而IL-10水平显著高于对照组(
P
<
0.01)
。
2组患者术后并发症及不良反应发生率比较,差异均无统计学意义(
P
>
0.05)。
结论
2
对于接受胸腔镜手术的患者,在术后24 h实施超声引导下的前锯肌平面二次阻滞,能有效延长术后镇痛时间,改善术后恢复质量,减少阿片类药物的用量,并有助于减轻机体的术后炎症反应,促进患者康复。
Objective
2
To investigate the effects of ultrasound-guided second serratus anterior plane block (SAPB) on postoperative analgesia, recovery quality, and inflammatory response in patients undergoing thoracoscopic surgery.
Methods
2
A total of 86 patients who underwent elective thoracoscopic surgery in Xiaog
an Central Hospital from August 2022 to June 2023 were selected and randomly divided into the serratus anterior plane block (SAPB) group(
n
=43) and the control group (
n
=43) by random number table method. All patients in both groups received the first ultrasound-guided SAPB during surgery. At 24 hours postoperatively, patients in the SAPB group received a ultrasound-guided second SAPB, while patients in the control group were injected with an equal volume of normal saline at the same site. The quality of recovery-40 (QoR-40) scores at 24 hours preoperatively, 48 hours and 72 hours postoperatively, numerical rating scale (NRS) scores of pain at 24 hours, 48 hours, 72 hours postoperatively, sufentanil consumption within 48 hours postoperatively, and serum levels of interleukin-6 (IL-6) and interleukin-10 (IL-10), as well as the incidences of postoperative complications and adverse reactions were compared between the two groups.
Results
2
Variance analysis of repeated measures data showed significant differences in the groups, time, and interaction effects for QoR-40 total scores (
P
<
0.05). Post-hoc tests revealed that the QoR-40 scores at 48 hours and 72 hours postoperatively in the SAPB group were significantly higher than those in the control group (
P
<
0.05). Regarding pain control,the NRS scores showed statistically significant differences in group, time, and interaction (
P
<
0.001). The NRS scores at 48 hours postoperatively and sufentanil consumption in the SAPB group were significantly lower/less than those in the control group(
P
<
0.05). In terms of inflammatory response, the IL-6 levels at 48 hours and 72 hours postoperatively in the SAPB group were significantly lower than those in the control group(
P
<
0.01), while the IL-10 levels were significantly higher than those in the control group(
P
<
0.01). There was no statistically significant
difference in the incidence of postoperative complications or adverse reactions between the two groups (
P
>
0.05).
Conclusion
2
For patients undergoing thoracoscopic surgery, performing ultrasound-guided second SAPB at 24 hours postoperatively can effectively prolong postoperative analgesia duration, improve postoperative recovery quality, reduce opioid consumption,alleviate postoperative inflammatory response, thereby promoting patient rehabilitation.
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