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1.南京市职业病防治院放射科,江苏 南京 210000
2.南京市职业病防治院药剂科,江苏 南京 210000
3.铜仁市人民医院放射科,贵州 铜仁 554300
收稿日期:2024-11-18,
纸质出版日期:2025-09-25
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王迅,涂雷,周思佳.多层螺旋CT对不同性质肺结节的诊断价值分析[J].局解手术学杂志,2025,34(09):809-812.
WANG Xun,TU Lei,ZHOU Si-jia.Diagnostic value of multi-slice spiral CT in pulmonary nodules of different properties[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2025,34(09):809-812.
王迅,涂雷,周思佳.多层螺旋CT对不同性质肺结节的诊断价值分析[J].局解手术学杂志,2025,34(09):809-812. DOI: 10.11659/jjssx.11E024087.
WANG Xun,TU Lei,ZHOU Si-jia.Diagnostic value of multi-slice spiral CT in pulmonary nodules of different properties[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2025,34(09):809-812. DOI: 10.11659/jjssx.11E024087.
目的
2
探讨多层螺旋CT对不同性质肺结节的诊断价值。
方法
2
收集2022年10月至2023年10月在铜仁市人民医院接受治疗的150例肺结节患者的临床资料进行回顾性研究,所有患者均接受多层螺旋CT检查,并以肺穿刺活检结果进行良恶性分组,对比良性肺结节患者和恶性肺结节患者的CT影像学特征以及CT灌注参数差异,评估多层螺旋CT对良恶性肺结节的诊断价值。
结果
2
肺穿刺活检结果显示,150例肺结节患者中恶性结节患者62例(恶性结节组),良性结节患者88例(良性结节组)。恶性结节组患者钙化占比明显低于良性结节组,而空泡征、分叶征、棘状突起、毛刺征占比明显高于良性结节组,差异均有统计学意义(
P
<
0.05)。恶性结节组和良性结节组患者平均通过时间(MTT)对比,差异无统计学意义(
P
>
0.05);恶性结节组患者血流量(BF)、血容量(BV)及表面通透性(PS)明显高于良性结节组,差异均有统计学意义(
P
<
0.05)。以肺结节患者肺穿刺活检结果作为金标准,多层螺旋CT对恶性结节的诊断准确度为94.00%,诊断敏感度为95.16%,诊断特异度为93.18%,阳性预测值为90.77%,阴性预测值为96.47%。
结论
2
不同性质的肺结节患者CT影像学特征和灌注参数存在显著差异,多层螺旋CT可有效鉴别肺结节良恶性,且具有较好的诊断效能。
Objective
2
To explore the diagnostic value of multi-slice spiral CT in pulmonary nodules of different properties.
Methods
2
The clinical data of 150 patients with pulmonary nodules who were treated at Tongren People's Hospital from October 2022 to October 2023 were collected for a retrospective study. All patients underwent multi-slice spiral CT examinations, and the benign and malignant grouping was conducted based on the results of lung biopsy. The CT imaging characteristics and CT perfusion parameters of patients with benign pulmonary nodulesand malignant pulmonary nodules were compared, and the diagnostic value of multi-slice spiral CT for benign and malignant pulmonary nodules was evaluated.
Results
2
The results of lung biopsy showed that among the 150 patients with pulmonary nodules, there were 62 patients with malignant pulmonary nodules (malignant nodule group) and 88 patients with benign pulmonary nodules (benign nodule group). The proportion of calcification patients in the malignant nodule group was significantly lower than that in the benign nodule group, while the proportions of patients with vacuolar sign, lobulation sign, spinous protrusion, and spiculation sign were significantly higher than those in the benign nodule group, and the differences were statistically significant (
P
<
0.05). There was no statistically significant difference in the mean transit time (MTT) between the malignant nodule group and the benign nodule group (
P
>
0.05). The blood flow (BF), blood volume (BV), and permeability surface(PS) of patients in the malignant nodule group were significantly higher than those in the benign nodule group, and the differences were statistically significant (
P
<
0.05). Taking the lung biopsy results of patients with pulmonary nodules as the gold standard, the diagnostic accuracy of multi-slice spiral CT for malignant nodules was 94.00%, the diagnostic sensitivity was 95.16%, the diagnostic specificity was 93.18%, the positive predictive value was 90.77%, and the negative predictive value was 96.47%.
Conclusion
2
There are significant differences in CT imaging features and perfusion parameters among patients with pulmonary nodules of different properties. Multi-slice spiral CT can effectively distinguish benign and malignant pulmonary nodules and has good diagnostic efficiency.
冯旭霞 , 张梅 , 吴丙琳 , 等 . 高分辨CT联合血清CEA、NSE在鉴别诊断良恶性孤立性肺结节中的应用价值 [J]. 中国CT和MRI杂志 , 2020 , 18 ( 6 ): 38 - 40 . doi: 10.3969/j.issn.1672-5131.2020.06.012 http://dx.doi.org/10.3969/j.issn.1672-5131.2020.06.012 .
Ma ZJ , Ma ZX , Sun YL , et al . Prediction of subsolid pulmonary nodule growth rate using radiomics [J]. BMC Med Imaging , 2023 , 23 ( 1 ): 177 . doi: 10.1186/s12880-023-01143-x http://dx.doi.org/10.1186/s12880-023-01143-x .
喻晖 , 齐佳 . PET/CT联合血清肿瘤标志物检测对孤立性肺结节良恶性的诊断价值 [J]. 中国CT和MRI杂志 , 2022 , 20 ( 7 ): 61 - 63 . doi: 10.3969/j.issn.1672-5131.2022.07.020 http://dx.doi.org/10.3969/j.issn.1672-5131.2022.07.020 .
Fu BJ , Lv FJ , Li WJ , et al . Significance of intra-nodular vessel sign in differentiating benign and malignant pulmonary ground-glass nodules [J]. Insights Imaging , 2021 , 12 ( 1 ): 65 . doi: 10.1186/s13244-021-01012-7 http://dx.doi.org/10.1186/s13244-021-01012-7 .
陈凤芳 , 马俊 , 王琳 , 等 . Ⅱ期结节病中SACE与免疫炎症指标、影像表现及肺功能的相关性研究 [J]. 国际呼吸杂志 , 2020 , 40 ( 12 ): 922 - 928 . doi: 10.3760/cma.j.cn131368-20191226-00039 http://dx.doi.org/10.3760/cma.j.cn131368-20191226-00039 .
Zhang R , Tian P , Qiu Z , et al . The growth feature and its diagnostic value for benign and malignant pulmonary nodules met in routine clinical practice [J]. J Thorac Dis , 2020 , 12 ( 5 ): 2019 - 2030 . doi: 10.21037/jtd-19-3591 http://dx.doi.org/10.21037/jtd-19-3591 .
鄢骑兵 , 喻茂文 , 谭辉 . 良恶性肺结节患者的CT影像学指标、血清学指标及呼出气体中VOCs的差异 [J]. 影像科学与光化学 , 2023 , 41 ( 1 ): 147 - 152 . doi: 10.7517/issn.1674-0475.221005 http://dx.doi.org/10.7517/issn.1674-0475.221005 .
曹冠杰 , 史志涛 , 王彩华 , 等 . CT放射组学联合血清肿瘤标志物对不确定性质肺结节恶性风险的预测价值 [J]. 临床肺科杂志 , 2023 , 28 ( 9 ): 1321 - 1326 . doi: 10.3969/j.issn.1009-6663.2023.09.005 http://dx.doi.org/10.3969/j.issn.1009-6663.2023.09.005 .
张啸波 , 肖越勇 , 张肖 , 等 . 针道封堵技术预防CT引导下经皮穿刺肺结节射频消融同步活检出血 [J]. 中国介入影像与治疗学 , 2021 , 18 ( 1 ): 13 - 17 . doi: 10.13929/j.issn.1672-8475.2021.01.004 http://dx.doi.org/10.13929/j.issn.1672-8475.2021.01.004 .
Zhao X , Xia Y , Li C , et al . Efficacy evaluation on the color Doppler ultrasound,multislice spiral CT combined with serum markers in diagnosis of primary hepatic carcinoma [J]. Iran J Public Health , 2021 , 50 ( 8 ): 1603 - 1612 . doi: 10.21037/jtd-19-3591 http://dx.doi.org/10.21037/jtd-19-3591 .
Wang SQ , Ren FY , Wang JH , et al . Diagnostic value of multislice spiral computed tomography (CT) combined with CT angiography for intra-abdominal undescended testis secondary seminomas [J]. Cancer Imaging , 2019 , 19 ( 1 ): 24 . doi: 10.1186/s40644-019-0210-z http://dx.doi.org/10.1186/s40644-019-0210-z .
马 宇 . 慢性脑供血不足患者脑血流变化的多层螺旋CT灌注成像研究 [J]. 影像技术 , 2023 , 35 ( 1 ): 16 - 20 .
曾小飞 , 吴鹏举 , 伍治强 , 等 . CT引导下肺结节定位针定位在肺结节中的应用研究 [J]. 局解手术学杂志 , 2022 , 31 ( 9 ): 804 - 808 . doi: 10.11659/jjssx.03E022041 http://dx.doi.org/10.11659/jjssx.03E022041 .
潘亚男 , 桑银洲 , 马永峰 , 等 . Myrian影像后处理系统在孤立性肺结节定性诊断中的应用及影像学特征分析 [J]. 影像研究与医学应用 , 2021 , 5 ( 17 ): 66 - 67 . doi: 10.3969/j.issn.1672-5131.2022. 09.025 http://dx.doi.org/10.3969/j.issn.1672-5131.2022.09.025 .
李勇平 , 雷傲利 , 李文革 , 等 . 应用MSCT三维重建提高对良、恶性孤立性肺结节诊断准确率研究 [J]. 中国CT和MRI杂志 , 2022 , 20 ( 2 ): 51 - 52 . doi: 10.3969/j.issn.1672-5131.2022.02.017 http://dx.doi.org/10.3969/j.issn.1672-5131.2022.02.017 .
张有智 , 郝显华 , 赵空军 , 等 . 老年人CT引导下经皮肺穿刺活检术的临床应用价值探讨 [J]. 中国实用医药 , 2022 , 17 ( 1 ): 12 - 15 . doi: 10.14163/j.cnki.11-5547/r.2022.01.004 http://dx.doi.org/10.14163/j.cnki.11-5547/r.2022.01.004 .
Tsoi KM , Lowe M , Tsuda Y , et al . How are indeterminate pulmonary nodules at diagnosis associated with survival in patients with high-grade osteosarcoma [J]. Clin Orthop Relat Res , 2021 , 479 ( 2 ): 298 - 308 . doi: 10.1097/CORR.0000000000001491 http://dx.doi.org/10.1097/CORR.0000000000001491 .
周研 , 张建平 , 耿仲伟 , 等 . 解剖性肺段切除术与肺叶切除术治疗磨玻璃结节样非小细胞肺癌的疗效分析 [J]. 局解手术学杂志 , 2022 , 31 ( 3 ): 198 - 201 . doi: 10.11659/jjssx.07E021056 http://dx.doi.org/10.11659/jjssx.07E021056 .
Fu Y , Zhang YY , Cui LG , et al . Ultrasound-guided biopsy of pleural-based pulmonary lesions by injection of contrast-enhancing drugs [J]. Front Pharmacol , 2019 , 10 ( 1 ): 960 . doi: 10.3389/fphar.2019. 00960 http://dx.doi.org/10.3389/fphar.2019.00960 .
Yankelevitz DF , Yip R , Henschke CI . Impact of duration of diagnostic workup on prognosis for early lung cancer [J]. J Thorac Oncol , 2023 , 18 ( 4 ): 527 - 537 . doi: 10.1016/j.jtho.2022.12.020 http://dx.doi.org/10.1016/j.jtho.2022.12.020 .
王晓燕 , 肖继伟 , 万钰磊 , 等 . 多层螺旋CT对肺小结节的诊断价值分析 [J]. 中华肺部疾病杂志 (电子版), 2019 , 12 ( 2 ): 197 - 199 . doi: 10.3969/j.issn.1005-1457.2019.02.008 http://dx.doi.org/10.3969/j.issn.1005-1457.2019.02.008 .
钱坤 , 赵昕 , 谭晓刚 , 等 . 电子计算机断层扫描引导下经皮肺穿刺活检磨玻璃结节的诊断价值 [J]. 首都医科大学学报 , 2022 , 43 ( 4 ): 558 - 563 . doi: 10.3969/j.issn.1006-7795.2022.04.008 http://dx.doi.org/10.3969/j.issn.1006-7795.2022.04.008 .
张玉霖 , 敖平 , 朱丽 , 等 . 基于多层螺旋CT对康北地区藏族人群叉状肋骨的研究 [J]. 局解手术学杂志 , 2024 , 33 ( 5 ): 404 - 407 . doi: 10.11659/jjssx.08E023052 http://dx.doi.org/10.11659/jjssx.08E023052 .
韩莉 , 赵云景 . 多层螺旋CT对肺部结节影像诊断价值分析 [J]. 中国实用医药 , 2023 , 18 ( 15 ): 88 - 91 . doi: 10.14163/j.cnki.11-5547/r.2023.15.024 http://dx.doi.org/10.14163/j.cnki.11-5547/r.2023.15.024 .
Zegadło A , Różyk A , Żabicka M , et al . Dual-energy computed tomo-graphy as a lower radiation dose alternative to perfusion computed tomography in tumor viability assessment [J]. Sci Rep , 2023 , 13 ( 1 ): 120 . doi: 10.1038/s41598-022-27221-8 http://dx.doi.org/10.1038/s41598-022-27221-8 .
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