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1.西安市人民医院/西安市第四医院疼痛科,陕西 西安 710004
2.陕西省血液中心体采一科,陕西 西安 710061
3.空军军医大学第二附属医院骨科,陕西 西安 710038
4.西安市人民医院/西安市第四医院脊柱外科,陕西 西安 710004
张伟亮,E-mail:1211261572@qq.com
收稿:2025-10-09,
网络首发:2026-07-24,
纸质出版:2026-07-25
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马晓亮,张铃浩,张弘韬等.老年腰椎管狭窄患者经皮脊柱内镜单侧椎板切开双侧减压术后隐性失血的危险因素分析[J].局解手术学杂志,2026,35(07):574-578.
MA Xiao-liang,ZHANG Ling-hao,ZHANG Hong-tao,et al.Risk factors for hidden blood loss after percutaneous endoscopic unilateral laminotomy for bilateral decompression in elderly patients with lumbar spinal stenosis[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(07):574-578.
马晓亮,张铃浩,张弘韬等.老年腰椎管狭窄患者经皮脊柱内镜单侧椎板切开双侧减压术后隐性失血的危险因素分析[J].局解手术学杂志,2026,35(07):574-578. DOI: 10.11659/jjssx.10E025011.
MA Xiao-liang,ZHANG Ling-hao,ZHANG Hong-tao,et al.Risk factors for hidden blood loss after percutaneous endoscopic unilateral laminotomy for bilateral decompression in elderly patients with lumbar spinal stenosis[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(07):574-578. DOI: 10.11659/jjssx.10E025011.
目的
2
探讨经皮脊柱内镜单侧椎板切开双侧减压术(Endo-ULBD)治疗老年腰椎管狭窄症(LSS)患者术后隐性失血(HBL)的发生及危险因素。
方法
2
回顾性分析西安市人民医院216例接受单节段Endo-ULBD治疗的老年LSS患者的临床资料,采用Gross公式计算术后HBL。采用单因素分析和
Spearman
秩相关分析筛选与HBL相关的因素;构建多因素线性回归模型分析HBL的独立相关因素。采用
Logistic
回归分析高HBL的危险因素,并评估模型的判别能力和校准度。
结果
2
216例患者术后HBL为372.51(322.46,409.23)mL,占总失血量(TBL)的89.32%。单因素分析发现,高血压、骨量减少或骨质疏松患者术后HBL更高(
P
<
0.05);
Spearman
秩相关分析显示,手术时间及BMI与HBL呈正相关(
P
<
0.01)。多因素线性回归分析显示,手术时间(
B
=0.002,
β
=0.439,
P
<
0.001)、BMI(
B
=0.007,
β
=0.151,
P
=0.015)与术后HBL独立相关。进一步
Logistic
回归分析显示,手术时间是高HBL的独立危险因素(
OR
=1.030,95%
CI
:1.018~1.042,
P
<
0.001);受试者工作特征(
ROC
)曲线分析显示,多因素
Logistic
回归预测模型的曲线下面积(
AUC
)为0.764(95%
CI
:0.701~0.823),校准曲线显示模型拟合尚可。
结论
2
老年LSS患者经Endo-ULBD治疗后HBL较高。手术时间延长和BMI较高与术后HBL增加独立相关;其中手术时间是高HBL的独立危险因素。多因素
Logistic
回归预测模型具有中等判别能力和可接受校准度,但仍需外部验证。
Objective
2
To investigate the occurrence and risk factors of hidden blood loss (HBL) after percutaneous endoscopic unilateral laminotomy for bilateral decompression (Endo-ULBD) in elderly patients with lumbar spinal stenosis (LSS).
Methods
2
The clinical data of 216 elderly patients with LSS who underwent single‑segment Endo‑ULBD at Xi'an People's Hospital were retrospectively analyzed.The postoperative HBL was estimated using the Gross formula. Univariate analysis and
Spearman
rank correlation analysis were performed to screen factors associated with HBL. A multivariate linear regression model was constructed to identify the independent factors associated with HBL.
Logistic
regression was conducted to analyze risk factors for high HBL, and the model's discriminative ability and calibration were evaluated.
Results
2
The postoperative HBL in the 216 patients was 372.51 (322.46, 409.23)mL, accounting for 89.32% of the total blood loss (TBL). Univariate analysis indicated that patients with hypertension, osteopenia or osteoporosis had significantly higher levels of postoperative HBL (
P
<
0.05).
Spearman
rank correlation analysis revealed that operative time and BMI were positively correlated with HBL (
P
<
0.01). Multivariate linear regression analysis demonstrated that operative time (
B
=0.002,
β
=0.439,
P
<
0.001) and BMI (
B
=0.007,
β
=0.151,
P
=0.015) were identified as independent factors associated with postoperative HBL. Further
Logistic
regression analysis demonstrated that operative time was an independent risk factor for high HBL (
OR
=1.030, 95%
CI
:1.018 to 1.042,
P
<
0.001).
Receiver operating characteristic
(
ROC
) curve analysis showed that the
area under the curve
(
AUC
) of the multivariate
Logistic
regression prediction model was 0.764 (95%
CI
: 0.701 to 0.823), and the calibration curve indicated acceptable model fit.
Conclusion
2
Postoperative HBL accounted for a considerable proportion in elderly LSS patients undergoing Endo‑ULBD. Prolonged operative time and higher BMI were independently associated with increased postoperative HBL, with operative time identified as an independent risk factor for high HBL. The multivariate
Logistic
regression prediction model demonstrated moderate discriminative ability and acceptable calibration, although external validation is still required.
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