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1.江苏省人民医院宿迁医院骨科, 江苏 宿迁 223800
2.南京鼓楼医院集团宿迁医院神经内科,江苏 宿迁 223800
马晓娇,E-mail:xululu1000@163.com
收稿:2025-09-02,
纸质出版:2026-05-25
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徐露露,马晓娇,尚婷婷等.术前营养状况对老年患者有创机械通气髋关节置换术后肺部感染的影响[J].局解手术学杂志,2026,35(05):437-440.
XU Lu-lu,MA Xiao-jiao,SHANG Ting-ting,et al.Effect of preoperative nutritional status on postoperative pulmonary infection in elderly patients undergoing hip arthroplasty with invasive mechanical ventilation[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(05):437-440.
徐露露,马晓娇,尚婷婷等.术前营养状况对老年患者有创机械通气髋关节置换术后肺部感染的影响[J].局解手术学杂志,2026,35(05):437-440. DOI: 10.11659/jjssx.09E025007.
XU Lu-lu,MA Xiao-jiao,SHANG Ting-ting,et al.Effect of preoperative nutritional status on postoperative pulmonary infection in elderly patients undergoing hip arthroplasty with invasive mechanical ventilation[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(05):437-440. DOI: 10.11659/jjssx.09E025007.
目的
2
明确术前营养状况对老年患者有创机械通气髋关节置换术后肺部感染的影响。
方法
2
选取江苏省人民医院宿迁医院全身麻醉下有创机械通气行髋关节置换术的老年患者249例为研究对象,根据术前1 d微型营养评定简表(MNA-SF)评分分组,将评分在12~14分的患者纳入正常组(
n
=158),12分的患者纳入低分组(
n
=91)。对2组患者手术前后血红蛋白(Hb)、白蛋白(ALB)、前白蛋白(PA)、肿瘤坏死因子(TNF-α)、白细胞介素-6(IL-6)、白细胞计数(WBC)、C反应蛋白(CRP)及中性粒细胞百分比(NP)进行比较。比较2组患者术后肺部感染及相关症状发生情况。
结果
2
术前1 d和术后1 d,低分组患者的Hb、ALB及PA水平均显著低于正常组(
P
0.05);术后1 d,低分组患者的TNF-α、IL-6、WBC、CRP及NP水平均显著高于
正常组(
P
0.05)。低分组患者术后体温38 ℃、气道有脓性分泌物、WBC异常、肺部湿啰音或实变体征及术后肺部感染发生率均显著高于正常组(
P
0.05)。
结论
2
术前营养评分较低的老年患者抵抗力较差,行有创机械通气髋关节置换术后易出现炎症和感染,增加肺部感染风险。
Objective
2
To clarify the impact of preoperative nutritional status on postoperative pulmonary infection in elderly patients undergoing hip arthroplasty with invasive mechanical ventilation.
Methods
2
A total of 249 elderly patients who received hip arthroplasty under general anesthesia with invasive mechanical ventilation at Suqian Hospital of Jiangsu Province People's Hospital were enrolled in this study. According to the mini nutritional assessment short form (MNA-SF) scores evaluated 1 day before surgery, patients with scores ranging from 12 to 14 points were assigned to the normal group (
n
=158),and those with scores below 12 points were assigned to the low-score group (
n
=91).The levels of hemoglobin (Hb),albumin (ALB), prealbumin (PA), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), white blood cell count (WBC), C-reactive protein (CRP), and neutrophil percentage (NP) before and after surgery were compared between the two groups. The two groups were compared in terms of the occurrence of postoperative pulmonary infection and related symptoms.
Results
2
The levels of Hb,ALB,and PA 1 day before surgery and 1 day after surgery in the low-score group were significantly lower than those in the normal group (
P
0.05);the levels of TNF-α, IL-6, WBC, CRP, and NP 1 day after surgery in the low-score group were significantly higher than those in the normal group (
P
0.05). The proportions of patients with body temperature38 ℃, purulent airway secretions, abnormal WBC, pulmonary moist rales or consolidation signs, and postoperative pulmonary infection after surgery in the low-score group were significa
ntly higher than those in the normal group(
P
0.05).
Conclusion
2
Elderly patients with low preoperative nutritional scores have poor resistance, and are prone to inflammation and infection after undergoing hip arthroplasty with invasive mechanical ventilation, thus increasing the risk of pulmonary infection.
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