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无锡市第二中医医院泌尿外科,江苏 无锡 214000
杨 磊,E-mail:yang_jian_long@163.com
收稿:2025-04-02,
纸质出版:2026-02-25
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曹海兵,杨磊,丁景泉.可弯曲负压吸引鞘在输尿管软镜治疗肾结石中的应用[J].局解手术学杂志,2026,35(02):149-152.
CAO Hai-bing,YANG Lei,DING Jing-quan.Application of flexible negative pressure suction sheath in the treatment of kidney stones with ureteroscopy[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(02):149-152.
曹海兵,杨磊,丁景泉.可弯曲负压吸引鞘在输尿管软镜治疗肾结石中的应用[J].局解手术学杂志,2026,35(02):149-152. DOI: 10.11659/jjssx.04E025054.
CAO Hai-bing,YANG Lei,DING Jing-quan.Application of flexible negative pressure suction sheath in the treatment of kidney stones with ureteroscopy[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(02):149-152. DOI: 10.11659/jjssx.04E025054.
目的
2
探究输尿管软镜联合可弯曲负压吸引鞘对肾结石患者结石清除率及生活质量的影响。
方法
2
回顾性分析我院收治的98例肾结石患者的临床资料,将行输尿管软镜联合可弯曲负压吸引鞘的患者作为可弯曲组(41例),行输尿管软镜联合普通输尿管软镜鞘的患者作为普通组(57例)。比较2组患者手术时间、术中出血量、住院时间、结石清除率。评估术前及术后2周2组患者的疼痛视觉模拟量表(VAS)评分及生活质量健康调查简表(SF-36)评分。检测2组患者术前及术后2周的超氧化物歧化酶(SOD)、丙二醛(MDA)、血浆皮质醇(Cor)、白细胞介素-6(IL-6)及降钙素原(PCT)水平。统计2组患者在治疗期间的并发症发生情况。
结果
2
可弯曲组患者的手术时间、术中出血量、住院时间均短/少于普通组(
P
<
0.05),结石清除率高于普通组(
P
<
0.05)。术后2周,2组患者的VAS评分均较术前显著下降(
P
<
0.05),但组间差异无统计学意义(
P
>
0.05)。术后2周,2组患者的SF-36评分均较术前显著升高(
P
<
0.05),且可弯曲组显著高于普通组(
P
<
0.05)。与术前比较,2组患者术后2周的SOD水平下降(
P
<
0.05),Cor、IL-6、MDA、PCT水平升高(
P
<
0.05);术后2周,可弯曲组患者的SOD水平高于普通组(
P
<
0.05),Cor、IL-6、MDA、PCT水平低于普通组(
P
<
0.05)。2组患者的并发症总发生率比较,差异无统计学意义(
P
>
0.05)。
结论
2
输尿管软镜联合可弯曲负压吸引鞘可提高肾结石患者的结石清除石率,更好地维持机体的抗氧化能力,并降低炎症与应激相关因子水平的过度升高,进而有效减轻手术引发的机体过度应激反应,提高患者生活质量。
Objective
2
To investigate the effects of ureteroscopy combined with flexible negative pressure suction sheath on stone clearance rate and quality of life in patients with kidney stones.
Methods
2
The clinical data of 98 patients with kidney stones admitted to our hospital were retrospectively analyzed.The patients who underwent ureteroscopy combined with flexible negative pressure suction sheath were selected as the flexible group (41 cases),and the patients who underwent ureteroscopy combined with ordinary ureteroscopic sheath were selected as the ordinary group (57 cases).The operation time,intraoperative blood loss,hospitalization time,and stone clearance rate were compared between the two groups.The visual analogue scale (VAS) scores for pain and the 36-item short form (SF-36) scores for quality of life of patients in the two groups were evaluated before operation and 2 weeks after operation.The levels of superoxide dismutase (SOD),malondialdehyde (MDA),plasma cortisol (Cor),interleukin-6 (IL-6) and procalcitonin (PCT) of patients in the two groups were detected before operation and 2 weeks after operation.The complications of patients in the two groups during the treatment period were counted.
Results
2
The operation time,intraoperative blood loss and hospitalization time of patients in the flexible group were shorter/less than those in the ordinary group (
P
<
0.05),and the stone clearance rate was higher than that in the ordinary group (
P
<
0.05).At 2 weeks after operation,the VAS scores of patients in the two groups were significantly lower than those before operation (
P
<
0.05),but there was no significant difference between the two groups (
P
>
0.05).At 2 weeks after operation,the SF-36 scores of patients in the two groups were significantly higher than those before operation (
P
<
0.05),and the SF-36 scores of patients in the flexible group were significantly higher than those in the ordinary group (
P
<
0.05).Compared with those before operation,the SOD levels of patients in the two groups decreased 2 weeks after operation (
P
<
0.05),while the Cor,IL-6,MDA and PCT levels increased (
P
<
0.05).Two weeks after operation, the SOD level of patients in the flexible group was higher than that in the ordinary group (
P
<
0.05),and the levels of Cor,IL-6,MDA,and PCT were lower than those in the ordinary group (
P
<
0.05).There was no significant difference in the incidence of complications between the two groups (
P
>
0.05).
Conclusion
2
The combination of ureteroscopy and flexible negative pressure suction sheath can significantly increase the stone clearance rate in patients with kidney stones,better maintain the body's antioxidant capacity, and reduce the excessive increase in the levels of inflammatory and stress-related factors, thereby effectively alleviating the excessive stress response of the body caused by surgery and improving the quality of life of patients.
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