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凉山彝族自治州第一人民医院耳鼻咽喉头颈外科,四川 西昌 615000
李艺梅,E-mail:17091175@qq.com
收稿:2025-04-10,
纸质出版:2026-05-25
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李艺梅,石柱,熊灵峰等.钆造影核磁共振成像在梅尼埃病内耳膜迷路积水诊断中的应用[J].局解手术学杂志,2026,35(05):388-392.
LI Yi-mei,SHI Zhu,XIONG Ling-feng,et al.Application of gadolinium-enhanced magnetic resonance imaging in the diagnosis of endolymphatic hydrops of the inner ear in Meniere´s disease[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(05):388-392.
李艺梅,石柱,熊灵峰等.钆造影核磁共振成像在梅尼埃病内耳膜迷路积水诊断中的应用[J].局解手术学杂志,2026,35(05):388-392. DOI: 10.11659/jjssx.04E025049.
LI Yi-mei,SHI Zhu,XIONG Ling-feng,et al.Application of gadolinium-enhanced magnetic resonance imaging in the diagnosis of endolymphatic hydrops of the inner ear in Meniere´s disease[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(05):388-392. DOI: 10.11659/jjssx.04E025049.
目的
2
探究内耳钆造影核磁共振成像(MRI)在梅尼埃病患者内耳膜迷路积水诊断中的价值。
方法
2
选取78例就诊于我院的梅尼埃病患者为研究对象,分析钆造影MRI与临床诊断梅尼埃病患者内耳膜迷路积水的一致性,比较不同前庭及耳蜗积水程度患者的纯音听阈测试、耳蜗电图、眼震视图(VNG)及前庭诱发肌源性电位(VEMP)检查结果,分析前庭及耳蜗积水程度与上述指标的相关性。
结果
2
钆造影MRI诊断梅尼埃病患者内耳膜迷路积水的敏感度为91.30%,特异度为93.75%,准确率为92.31%,阳性预测值为95.45%,阴性预测值为88.24%,
Kappa
值为0.843,与临床诊断具有较高的一致性。重度前庭积水患者的纯音听阈值、VEMP异常率、VNG异常率显著高于轻度前庭积水及无前庭
积水的患者(
P
0.05),轻度前庭积水患者的纯音听阈值、VEMP异常率、VNG异常率显著高于无前庭积水的患者(
P
0.05),不同前庭积水程度的患者负性总和电位/动作电位(-SP/AP)值无统计学差异(
P
0.05)。重度耳蜗积水患者的纯音听阈值、-SP/AP值显著高于轻度耳蜗积水及无耳蜗积水的患者(
P
0.05),轻度耳蜗积水患者纯音听阈值、-SP/AP值显著高于无耳蜗积水的患者(
P
0.05),不同耳蜗积水程度的患者VEMP及VNG异常率比较,差异无统计学意义(
P
0.05)。
Spearman
相关系数分析显示,前庭积水程度与纯音听阈值、VEMP异常率及VNG异常率均呈显著正相关(
P
0.05),耳蜗积水程度与纯音听阈值及-SP/AP值均呈显著正相关(
P
0.05)。
结论
2
钆造影MRI可有效诊断梅尼埃病患者内耳膜迷路积水,明确积水位置和积水程度,且诊断结果与纯音听阈测试、耳蜗电图、眼震视图及VEMP检查结果相关,可用于辅助判断梅尼埃病病情,指导临床治疗。
Objective
2
To explore the application value of gadolinium-enhanced magnetic resonance imaging (MRI) in the diagnosis of endolymphatic hydrops of the inner ear in patients with Meniere's disease.
Methods
2
A total of 78 patients with Meniere's disease treated in our hospital were enrolled.The consistency between gadolinium-enhanced MRI and clinical diagnosis in identifying endolymphatic hydrops of the inner ear in patients with Meniere's disease was analyzed.The results of pure tone audiometry,electrocochleography, videonystagmography (VNG) and vestibular evoked myogenic potential (VEMP) were compared among patients with different degrees of vestibular and cochlear hydrops. The correlations of vestibular and cochlear hydrops severity with the above examination indicators were further analyzed.
Results
2
Gadolinium-enhanced MRI showed a sensitivity of 91.30%, a specificity of 93.75%, an accuracy of 92.31%, a positive predictive value of 95.45%, and a negative predictive value of 88.24% for diagnosing endolymphatic hydrops of the inner ear in patients with Meniere's disease, which had high consistency with the clinical diagnosis with a
Kappa
value of 0.843.The pure-tone threshold and the abnormal rates of VEMP and VNG in patients with severe ves
tibular hydrops were significantly higher than those in patients with mild vestibular hydrops or without vestibular hydrops (
P
0.05). Patients with mild vestibular hydrops also presented remarkably higher pure-tone threshold and abnormal rates of VEMP and VNG compared with those without vestibular hydrops (
P
0.05). There was no significant difference in the negative summating potential/action potential (-SP/AP) ratio among patients with different degrees of vestibular hydrops (
P
0.05).The pure-tone threshold and -SP/AP ratio in patients with severe cochlear hydrops were significantly higher than those in patients with mild cochlear hydrops or without cochlear hydrops(
P
0.05). The pure-tone threshold and -SP/AP ratio in patients with mild cochlear hydrops were also significantly increased compared with patients without cochlear hydrops (
P
0.05).No significant differences were found in the abnormal rates of VEMP and VNG among patients with different degrees of cochlear hydrops (
P
0.05).
Spearman
correlation analysis showed that the degree of vestibular hydrops was significantly positively correlated with pure-tone threshold, VEMP abnormal rate and VNG abnormal rate (
P
0.05);the degree of cochlear hydrops was significantly positively correlated with pure-tone threshold and -SP/AP ratio (
P
0.05).
Conclusion
2
Gadolinium-enhanced MRI can effectively diagnose endolymphatic hydrops of the inner ear in patients with Meniere's disease,and clarify the location and severity of hydrops.Its diagnostic results are correlated with pure tone audiometry, electrocochleography,VNG and VEMP results,which can assist in evaluating the condition of Meniere's disease and guiding clinical treatment.
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