
浏览全部资源
扫码关注微信
合肥市第二人民医院高压氧科,安徽 合肥 230011
周小妹,E-mail:554683678@qq.com
纸质出版日期:2025-02-25,
收稿日期:2024-02-04,
移动端阅览
钟宏丽, 许季祥, 周小妹. 高压氧治疗意识障碍合并气管切开的疗效评价[J]. 局解手术学杂志, 2025,34(2):143-146.
ZHONG HONG-LI, XU JI-XIANG, ZHOU XIAO-MEI. Clinical efficacy of hyperbaric oxygen therapy on patients with tracheostomy for consciousness disturbance. [J]. Journal of regional anatomy and operative surgery, 2025, 34(2): 143-146.
钟宏丽, 许季祥, 周小妹. 高压氧治疗意识障碍合并气管切开的疗效评价[J]. 局解手术学杂志, 2025,34(2):143-146. DOI: 10.11659/jjssx.02E024015.
ZHONG HONG-LI, XU JI-XIANG, ZHOU XIAO-MEI. Clinical efficacy of hyperbaric oxygen therapy on patients with tracheostomy for consciousness disturbance. [J]. Journal of regional anatomy and operative surgery, 2025, 34(2): 143-146. DOI: 10.11659/jjssx.02E024015.
目的
2
探究高压氧治疗意识障碍合并气管切开患者的临床效果和安全性。
方法
2
选取2019年1月至2021年12月在本院治疗意识障碍合并气管切开的60例患者为研究对象,将其随机分为对照组(30例)和治疗组(30例)。对照组患者给予气管切开治疗,同时进行原发病的一般治疗。治疗组患者在对照组的基础上使用高压氧治疗。治疗1个月后,比较2组患者的治疗总有效率、格拉斯哥昏迷指数(GCS)评分、植物状态诊断标准(PVS)评分、白细胞计数、中性粒细胞计数、血红蛋白、C反应蛋白(CRP)及不良反应发生情况。
结果
2
治疗组治疗总有效率(96.67%)高于对照组(76.67%),差异有统计学意义(
P
<
0.05)。2组患者治疗后的GCS评分和PVS评分均较治疗前增加(
P
<
0.05),且治疗组患者的GCS评分和PVS评分均高于对照组(
P
<
0.05)。2组患者治疗前后的白细胞计数水平比较,差异无统计学意义(
P
>
0.05);2组患者治疗后的中性粒细胞计数和CRP水平均低于治疗前(
P
<
0.05),且治疗组患者治疗后的中性粒细胞计数和CRP水平均低于对照组(
P
<
0.05);2组患者治疗后的血红蛋白水平均较治疗前升高(
P
<
0.05),且治疗组患者治疗后的血红蛋白水平高于对照组(
P
<
0.05)。治疗组患者的不良反应发生率(6.67%)低于对照组(26.67%),差异有统计学意义(
P
<
0.05)。
结论
2
高压氧治疗意识障碍合并气管切开患者的临床效果较好,安全性较高。
Objective
2
To explore the therapeutic effect and safety of hyperbaric oxygen therapy in the treatment of patients underwent tracheostomy for consciousness disturbance.
Methods
2
A total of 60 patients underwent tracheostomy for consciousness disturbance in our hospital from January 2019 to December 2021 were selected and randomly divided into the control group (30 cases) and the treatment group (30 cases). Patients in the control group were treated with tracheotomy and general treatment for primary disease, while patients in the treatment group were treated with hyperbaric oxygen on the basis of the control group. After 1 month of treatment, the total effective rate,Glasgow coma scale (GCS) score, persistent vegetative state (PVS) score, white blood cell count, neutrophil count, hemoglobin, C-reactive protein (CRP), and adverse reactions of patients were compared between the two groups.
Results
2
The total effectiv
e rate of the treatment group (96.67%) was higher than that of the control group (76.67%), and the difference was statistically significant (
P
<
0.05). The GCS and PVS scores of patients in the two groups increased compared with those before treatment(
P
<
0.05), and the GCS and PVS scores of patients in the treatment group were higher than those in the control group (
P
<
0.05). There was no statistically significant difference in white blood cell count of patients in the two groups before and after treatment (
P
>
0.05). The neutrophil count and CRP level of patients in both groups after treatment were lower than those before treatment(
P
<
0.05), and the neutrophil count and CRP levels of patients after treatment in the treatment group were lower than those in the control group (
P
<
0.05). The hemoglobin level of patients in both groups after treatment increased compared with those before treatment(
P
<
0.05), and the hemoglobin level of patients after treatment in the treatment group was higher than that in the control group (
P
<
0.05).The incidence of adverse reactions in the treatment group (6.67%) was lower than that in the control group (26.67%),and the difference was statistically significant (
P
<
0.05).
Conclusion
2
Hyperbaric oxygen therapy has a good therapeutic effect and high safety for patients who treated by tracheostomy for consciousness disturbance.
高压氧治疗意识障碍气管切开
hyperbaric oxygen therapyconsciousness disturbancetracheostomy
邹瑜聪,周静,林炜明,等. 近5年慢性意识障碍治疗的可视化分析[J]. 中国康复理论与实践,2023,29(9):1065-1071.doi:10.3969/j.issn.1006-9771.2023.09.010http://dx.doi.org/10.3969/j.issn.1006-9771.2023.09.010.
汤时蓝,谢可欣,刘玲谕,等. 慢性意识障碍患者康复预后及照护研究进展[J]. 中国全科医学,2023,26(27):3342-3348.doi:10.12114/j.issn.1007-9572.2023.0088http://dx.doi.org/10.12114/j.issn.1007-9572.2023.0088.
姚正琴.气管切开呼吸道护理相关因素的监测与管理[J].生命科学仪器,2023,21(z1):487-450.doi:10.11967/2023008446http://dx.doi.org/10.11967/2023008446.
黄欣. 循证护理对重症肺炎气管切开患者术后并发症及预后的影响[J]. 国际护理学杂志,2022,41(1):141-144.doi:10.3760/cma.j.cn221370-20200329-00038http://dx.doi.org/10.3760/cma.j.cn221370-20200329-00038.
Ciarlone GE, Hinojo CM, Stavitzski NM, et al. CNS function and dysfunction during exposure to hyperbaric oxygen in operational and clinical settings[J].Redox Biol,2019,27(1):1159-1163.doi:10.1016/j.redox.2019.101159http://dx.doi.org/10.1016/j.redox.2019.101159.
高瑜,陈图农,徐成,等. 美国《精神障碍诊断与统计手册》第5版(DSM-5)人格特质的稳定性和变化性研究[J]. 临床精神医学杂志,2021,31(1):42-46.doi:10.3969/j.issn.1005-3220.2021. 01.013http://dx.doi.org/10.3969/j.issn.1005-3220.2021.01.013.
王昕馨,杨宛凝,菅敏钰,等. 全身麻醉手术下慢性意识障碍患者的临床特征及意识改善预测[J]. 首都医科大学学报,2023,44(2):231-236.doi:10.3969/j.issn.1006-7795.2023.02.008http://dx.doi.org/10.3969/j.issn.1006-7795.2023.02.008.
李娅,秦天,李华娴,等. 高压氧治疗对高原低氧肺组织氧化损伤的影响[J]. 中华航海医学与高气压医学杂志,2023,30(4):516-520.doi:10.3760/cma.j.cn311847-20220909-00303http://dx.doi.org/10.3760/cma.j.cn311847-20220909-00303.
崔智杰,陈华辉,斯宝,等. GCS与CT评分对中重型颅脑损伤患者预后的评估[J]. 西部医学,2023,35(6):848-853.doi:10.3969/j.issn.1672-3511.2023.06.012http://dx.doi.org/10.3969/j.issn.1672-3511.2023.06.012.
张大海,白如玉,雷志刚,等. 唑吡坦对脑损伤植物状态患者促醒疗效的影响——评《中枢神经系统MRI和CT诊断图解》[J]. 中国辐射卫生,2020,29(5):580-582.
张谦,周腾飞,田新原,等. 脑卒中后气管切开患者的综合肺康复进展[J]. 中国康复,2023,38(2):106-110.doi:10.3870/zgkf. 2023.02.009http://dx.doi.org/10.3870/zgkf.2023.02.009.
邱琴.纳洛酮联合高压氧治疗急性一氧化碳中毒的临床效果[J].临床合理用药,2023,16(28):108-110.doi:10.15887/j.cnki. 13-1389/r.2023.28.032http://dx.doi.org/10.15887/j.cnki.13-1389/r.2023.28.032.
顾怀金,王建斌,何军,等. 丙泊酚联合利多卡因在ICU气管切开术中的镇静镇痛效果研究[J]. 局解手术学杂志,2023,32(9):809-813.doi:10.11659/jjssx.03E023172http://dx.doi.org/10.11659/jjssx.03E023172.
吕钦,孙峰,贾龙,等. 自制新型气切套管用雾化组件在气管切开患者中的应用效果[J]. 中国医药导报,2023,20(24):77-80.doi:10.20047/j.issn1673-7210.2023.24.18http://dx.doi.org/10.20047/j.issn1673-7210.2023.24.18.
罗欢欢,钱建锋,闵继康,等.高压氧在心肺复苏后脑复苏中的应用进展[J]. 护理研究,2023,37(16):2956-2958.doi:10.12102/j.issn.1009-6493.2023.16.018http://dx.doi.org/10.12102/j.issn.1009-6493.2023.16.018.
韩雪迎,焦鹏,宋玉华. 高压氧治疗对急性一氧化碳中毒合并吸入性肺炎患者康复的影响[J]. 中华航海医学与高气压医学杂志,2023,30(2):229-233.doi:10.3760/cma.j.cn311847-2021 0129-00039http://dx.doi.org/10.3760/cma.j.cn311847-20210129-00039.
翟登月,魏宁,吴波娜,等. GCS和NIHSS对基底动脉尖综合征临床转归的预测[J].中国神经精神疾病杂志,2010,36(3):141-144.doi:10.3969/j.issn.1002-0152.2010.03.004http://dx.doi.org/10.3969/j.issn.1002-0152.2010.03.004.
Ji Y, Qiu B, Gao S. The powered vascular staple (PVS) versus conventional powered linier cutter (PLC) for the application of bronchial transection in thoracoscopic anatomic segmentectomy[J].J Thorac Dis,2019,11(11):4647-4653.doi:10.21037/jtd.2019. 10.68http://dx.doi.org/10.21037/jtd.2019.10.68.
Shytle RD, Eve DJ, Kim SH, et al. Retrospective case series of traumatic brain injury and post-traumatic stress disorder treated with hyperbaric oxygen therapy[J].Cell Transplant,2019,28(7):885-892.doi:10.1177/0963689719853232http://dx.doi.org/10.1177/0963689719853232.
王克,包志军,张俊,等. 高压氧舱治疗颅脑外伤术后恶性脑水肿的临床效果研究[J]. 中国医学装备,2023,20(12):125-129. doi:10.3969/J.ISSN.1672-8270.2023.12.026http://dx.doi.org/10.3969/J.ISSN.1672-8270.2023.12.026.
张涛,王梦媛,刘子号,等. 高压氧辅助治疗对溃疡性结肠炎患者临床疗效及炎症因子影响的Meta分析[J]. 中华航海医学与高气压医学杂志,2024,31(2):200-206.doi:10.3760/cma.j.cn 311847-20211017-00279http://dx.doi.org/10.3760/cma.j.cn311847-20211017-00279.
0
浏览量
0
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构
京公网安备11010802024621