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1.江苏省人民医院宿迁医院急诊科,江苏 宿迁 223800
2.江苏省人民医院宿迁医院神经内科,江苏 宿迁 223800
曹虎男,E-mail:caohunan@smail.nju.edu.cn
收稿:2025-10-14,
网络首发:2026-07-24,
纸质出版:2026-07-25
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陈王静,曹虎男,孟庆林等.脑卒中患者急诊介入取栓手术后发生肺部感染的致病菌特征及术前营养相关危险因素分析[J].局解手术学杂志,2026,35(07):625-628.
CHEN Wang-jing,CAO Hu-nan,MENG Qing-lin,et al.Pathogenic bacteria features and preoperative nutrition‑related risk factors for pulmonary infection after emergency endovascular thrombectomy in stroke patients[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(07):625-628.
陈王静,曹虎男,孟庆林等.脑卒中患者急诊介入取栓手术后发生肺部感染的致病菌特征及术前营养相关危险因素分析[J].局解手术学杂志,2026,35(07):625-628. DOI: 10.09659/jjssx.10E025036.
CHEN Wang-jing,CAO Hu-nan,MENG Qing-lin,et al.Pathogenic bacteria features and preoperative nutrition‑related risk factors for pulmonary infection after emergency endovascular thrombectomy in stroke patients[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(07):625-628. DOI: 10.09659/jjssx.10E025036.
目的
2
明确脑卒中患者急诊介入取栓手术后肺部感染的发生状况、致病菌分布特点及术前营养相关影响因素。
方法
2
选取2022年7月至2025年6月江苏省人民医院宿迁医院因急性缺血性脑卒中行急诊介入取栓手术治疗的196例老年患者为研究对象,根据术后肺部感染发生情况分为感染组(
n
=47)和未感染组(
n
=149)。分析患者术后肺部感染的致病菌分布情况,比较2组患者术前营养状况指标并分析肺部感染的影响因素。
结果
2
196例患者中,发生肺部感染47例(23.98%);共分离培养出67株致病菌,其中革兰阴性菌检出43株(64.18%),占比最高。2组患者2002年营养风险筛查(NRS-2002)评分、危重症患者营养风险(NUTRIC)评分、总淋巴细胞计数及血红蛋白、总蛋
白、白蛋白水平比较,差异有统计学意义(
P
<
0.05),其余基线指标差异无统计学意义(
P
>
0.05)。多因素
Logistic
回归分析结果显示,NUTRIC评分≥5分、总蛋白
<
60 g/L及白蛋白
<
35 g/L为导致脑卒中患者急诊介入取栓手术后发生肺部感染的独立危险因素(
OR
>
1,
P
<
0.05)。
结论
2
脑卒中患者急诊介入取栓手术后肺部感染发生率较高,革兰阴性菌为其主要致病菌。术前NUTRIC评分较高、总蛋白及白蛋白水平较低的患者术后更容易发生肺部感染。
Objective
2
To investigate the incidence,distribution of pathogenic bacteria and preoperative nutrition‑related influencing factors of pulmonary infection after emergency endovascular thrombectomy in stroke patients.
Methods
2
A total of 196 elderly patients who underwent emergency endovascular thrombectomy for acute ischemic stroke at Suqian Hospital of Jiangsu Province People's Hospital from July 2022 to June 2025 were enrolled. They were divided into the infection group (
n
=47) and the non-infection group (
n
=149) according to the occurrence of postoperative pulmonary infection. The distribution of pathogenic bacteria after surgery was analyzed. The preoperative nutritional indicators were compared between the two groups,and risk factors for pulmonary infection were analyzed.
Results
2
Among the 196 patients, 47 cases (23.98%) developed pulmonary infection. A total of 67 strains of pathogenic bacteria were isolated, of which 43 strains (64.18%) were Gram‑negative bacteria, representing the highest proportion. Statistically significant differences were found between the two groups in nutritional risk screening 2002 (NRS-2002) score,nutrition risk in the critically ill (NUTRIC) score,total lymphocyte count and levels of hemoglobin,total protein,and albumin (
P
<
0.05), while no statistically significant differences were observed in the remaining baseline variables (
P
>
0.05). Multivariate
Logistic
regression analysis indic
ated that NUTRIC score≥5 points,total protein
<
60 g/L and albumin
<
35 g/L were independent risk factors for pulmonary infection after emergency endovascular thrombectomy in stroke patients(
OR
>
1,
P
<
0.05).
Conclusion
2
The incidence of pulmonary infection after emergency endovascular thrombectomy in stroke patients is relatively high,and Gram-negative bacteria are the predominant pathogenic bacteria. Patients with higher preoperative NUTRIC score,and lower levels of total protein and albumin are more susceptible to postoperative pulmonary infection.
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