JIA YAN, GAO BO. Biological safety of Ni-Cr alloy fabricated by laser solid forming technology. [J]. Journal of army medical university, 2009, 31(8): 668-671.
JIA YAN, GAO BO. Biological safety of Ni-Cr alloy fabricated by laser solid forming technology. [J]. Journal of army medical university, 2009, 31(8): 668-671.DOI:
Objective To evaluate the biological safety of a Ni-62.9Cr-23 alloy fabricated by laser solid forming technology. Methods According to the requirements of national standards GB/T16886-2003
YY/T0279-1995 and YY/T0244-1996
general cytotoxicity
acute systemic toxicity
hemolysis testing
oral mucous membrane irritation testing were used to evaluate the alloy. Results The alloy was indicated having no cytotoxicity and with a hemolytic rate of 0.385%. The oral mucous membrane irritation testing showed that the alloy had no mucous membrane irritation. The acute systemic toxicity test indicated that the alloy had no acute systemic toxicity. Conclusion The Ni-62.9Cr-23 alloy has good biological safety in a certain extent.