Objective    To evaluate the role of OMOM capsule endoscopy in diagnosis of colon diseases. Methods    Forty-six patients with suspected colon diseases

aged 18 to 68

voluntarily underwent the examination with the OMOM capsule endoscopy and colon endoscopy after informed the aim of the study. Patients who were suspected with colon stenosis or obstruction were excluded from the study. The outcome were compared with the results of common colonoscopy. The sensitivity

specificity and accuracy of OMOM capsule endoscopy were analyzed. Results    OMOM capsule endoscopic examination were completed successfully in 40 of 46 (87.0%) patients. For diagnosis of colon diseases with OMOM capsule endoscopy

the sensitivity was 57.7%

the specificity was 85.7%

and the accuracy was 67.5%. While

the positive predictive value was 88.2%

and the negative predictive value was 52.2%. The positive likelihood ratio was 4.04 and the negative likelihood ratio was 0.494. The bowel preparation had direct influence on examine. Polyethylene Glycol 4000 combined with 50% salamarum had better colon clearness. Conclusion    OMOM capsule endoscopy is a safe

non-invasive method

and can provide definitive diagnosis in colon diseases. The bowel preparation is important for successful examination.