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1. 第三军医大学军事预防医学院营养与食品安全研究中心,重庆市营养与食品安全重点实验室,重庆市医学营养研究中心
2. 第三军医大学新桥医院营养科,内分泌科
纸质出版日期:2011,
网络出版日期:2011-11-30,
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王建, 徐静, 王斌, 等. 绝经后妇女膳食结构与骨质疏松症发生的相关性研究[J]. 陆军军医大学学报, 2011,33(22):2397-2401.
WANG JIAN, XU JING, WANG BIN, et al. Correlation of postmenopausal osteoporosis risk with diet structure. [J]. Journal of army medical university, 2011, 33(22): 2397-2401.
目的 结合我国居民近年来膳食结构的改变,探讨现阶段膳食结构和营养素摄入水平对重庆市绝经后妇女骨质疏松症(postmenopausal osteoporosis ,PMOP)发生的影响。 方法 采用半定量食物频数问卷进行膳食调查,比较PMOP病例组与非PMOP对照组的膳食营养素和不同食物类别摄入水平差异性,并用非条件Logistic回归模型分析膳食营养素和食物类别摄入水平与PMOP发生的相关性。 结果 膳食中大豆蛋白(调整
OR
=0.291
95%
CI
=0.017~0.852)、维生素A (调整
OR
=0.671
95%
CI
=0.326~0.901)、维生素D (调整
OR
=0.412
95%
CI
=0.145~0.763)和钙(调整
OR
=0.352,95%
CI
=0.176~0.824)摄入水平与PMOP发生呈显著的负相关,而动物蛋白摄入水平(
OR
=2.316
95%
CI
=1.228~5.381)与PMOP发生呈显著正相关。PMOP组的大豆类(制品)、新鲜水果、深色蔬菜以及奶类的摄入量显著低于非PMOP组(
P
<
0.05),而烹饪油的摄入量显著高于非PMOP组(
P
<
0.05)。其余食物类别的摄入水平在两组之间无显著性差异(
P
>0.05)。高水平的豆制品(调整
OR
=0.562
95%
CI
=0.274~0.835)、深色蔬菜(
OR
=0.629,95%
CI
=0.418~0.925)、奶类(
OR
=0.594
95%
CI
=0.237~0.839)摄入与PMOP发生呈显著的负相关,而高水平的烹饪油摄入(
OR
=3.821
95%
CI
=1.479~7.738)与PMOP发生呈显著正相关。 结论 中老年女性在日常生活中增加大豆类、深色蔬菜和奶类食品的摄入可减少PMOP发生风险,而长期高水平摄入动物蛋白和烹调用油会增加PMOP发生的风险。
Objective To determine the correlation of postmenopausal osteoporosis (PMOP) in Chong
qing with the level of intake nutrients and change of diet structure. Methods Semi-quantitative Food Frequency Questionnaire was used to make a survey on a total of 460 Chongqing females (including 152 PMOP and 308 non-PMOP) during June 2007 to June 2008 for their dietary structure. The levels of intake nutrients and diet structure between PMOP group and non-PMOP control group were compared. Non-conditional logistic model was used to estimate the correlation between risk factors and PMOP. Results In diet structure
there were negative correlations of higher average daily dietary intake of soy derived protein (
OR
=0.291
95%
CI
=0.017-0.852)
Vit A (
OR
=0.671
95%
CI
=0.326-0.901)
Vit D (
OR
=0.412
95%
CI
=0.145-0.763)
calcium (
OR
=0.352
95%
CI
=0.176-0.824)
soy products (
OR
=0.629
95%
CI
=0.418-0.925)
dark colored vegetables (
OR
=0.629
95%
CI
=0.418-0.925) and milk (
OR
=0.594
95%
CI
=0.237-0.839) with the incidence of PMOP. Daily dietary intake levels of soy
fresh fruits
dark colored vegetables and milk in POMP group were lower than non-POMP group (
P
<
0.05)
and the daily dietary intake level of cooking oil in POMP group was higher than non-POMP group (
P
<
0.05). Conclusion Soy products
dark colored vegetables and milk can reduce the incidence of POMP. High level intake of animal derived protein and cooking oil can promote its incidence.
绝经后骨质疏松症膳食调查营养素膳食结构
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