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1. 重庆医科大学附属永川医院口腔科
2. 重庆医科大学附属口腔医院正畸科
纸质出版日期:2011,
网络出版日期:2011-11-30,
移动端阅览
张琳林, 单春城, 戴红卫, 等. 大鼠正畸牙根吸收修复早期的组织学观察[J]. 陆军军医大学学报, 2011,33(22):2394-2396.
ZHANG LINLIN, SHAN CHUNCHENG, DAI HONGWEI, et al. Histological observation of early reparative process of orthodontical tooth resorption in rats. [J]. Journal of army medical university, 2011, 33(22): 2394-2396.
目的 观察SD大鼠正畸牙根吸收后,早期修复过程中牙周组织的修复情况。 方法 选取72只雄性SD大鼠,加力14 d后拆除加力装置,分别在拆除加力装置后0、1、3、5、7、10、14 d和28 d处死,通过HE染色和扫描电镜观察牙周组织形态学变化,TRAP染色检测破牙骨质细胞在牙根周围的变化情况。 结果 随着加力装置拆除时间的延长,牙周组织中出现越来越多的修复相关性细胞,破牙骨质细胞在0~5 d实验组和对照组比较有统计学差异(
P
<
0.05),7~28 d实验组和对照组比较无统计学差异(
P
>0.05)。 结论 在拆除加力装置后,吸收的牙周组织逐渐发生不同程度的修复,随着时间的延长,修复越好。
Objective To investigate the repair situation of periodontal tissue during the repair process following experimentally induced tooth movement in SD rats. Methods The upper left first molars were moved mesially in 72 12-week-old male Wistar rats using a coil spring with a force of 0.49 N. After 14 d
the appliance was removed and the animals were killed in groups of 8 immediately after withdrawal of the force and 3
5
7
10
14
and 28 d later. Histological staining and scanning electron microscopy (SEM) were used to observe changes of periodontium histomorphology. Tartrate-resistant acid phosphatase (TRAP) staining was used to detect changes of cementoclast around the root. Results
There were more and more repair cells appearing in periodontal tissue after withdrewing the coils
and there was statistically significant differences in 0 to 5 days groups and control group(
P
<
0.05)
but not in 7 to 28 days group and control group (
P
>0.05). Conclusion Absorbent periodontal tissue will gradually complete a certain degree of repair after removing the force
and the longer the time is
the better the repair outcome.
牙根吸收牙根修复正畸牙移动
root resorptionroot repairorthodontic tooth movement
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