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南京中医药大学第三附属医院全国中医肛肠医疗中心
纸质出版日期:2013,
网络出版日期:2013-11-15,
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倪敏, 丁曙晴, 皇甫少华, 等. 功能性排便障碍患者经腰刺激运动诱发电位的研究[J]. 陆军军医大学学报, 2013,35(21):2292-2294.
NI MIN, DING SHUQING, HUANGPU SHAOHUA, et al. Translumbar motor-evoked potentials in diagnosis of functional defecation disorders. [J]. Journal of army medical university, 2013, 35(21): 2292-2294.
目的 探讨经腰磁刺激运动诱发电位对功能性排便障碍(functional defecation disorders
FDD)的诊断价值。 方法 收集2010年3月至2011年9月本院住院或门诊的FDD患者80例(男性37例,女性43例),年龄23~69(53.12±17.60)岁,病程(8.28±6.14)年;同期招募健康志愿者30例作为正常对照组(男性13例,女性17例),年龄19~35(25.67±7.32)岁。通过磁刺激腰骶部,记录肛门外括约肌动作电位潜伏期和波幅变化,观察腰脊神经根到肛门外括约肌的运动神经传导功能。 结果 正常对照组检测波幅为400~1 100(725.63±178.23)μV,潜伏期为2.6~3.7(3.35±0.41)ms。FDD组和正常对照组左右侧MEP各参数比较差异均无统计学意义(
P
>0.05);与正常对照组比较,FDD组波潜伏期延长,波幅下降,差异有统计学意义(
P
<
0.05)。 结论 经腰磁刺激运动诱发电位对功能性排便障碍的诊断具有重要价值。
Objective To evaluate the diagnostic value of translumbar magnetic stimulation motor evoked potentials for functional defecation disorders (FDD). Methods Eighty cases of FDD in- and out-patients in our department from March 2010 to September 2011 were enrolled in the study. Another 30 healthy volunteers were recruited during the same period. The patients were 37 males and 43 females
with a mean age of 53.12±17.60 (ranging from 23 to 69) and a mean course of 8.28±6.14 years. While the normal control group included 13 males and 17 females
with a mean age
of 25.67±7.32 (ranging from 19 to 35). Anorectal motor evoked potentials (MEP) was recorded after translumbar magnetic stimulation (TMS) over bilaterally lumbar nerve root to observe the motor nerve conduction in external anal sphincter. Results The amplitude of magnetic stimulation-lumbar motor evoked potentials (MS-LMEP) in the external anal sphincter was 725.63 ± 178.23 μV (ranging from 400 to 1 100)
and the latency was 3.35±0.412 ms (ranging from 6 to 3.7) in normal control. The amplitude was decreased
and the latency was prolonged compared with those of normal control (P>0.05). But there was no significant difference in both sides between the 2 groups (
P
<
0.05). Conclusion Translumbar magnetic stimulation motor evoked potentials have a significant value in the diagnosis of FDD.
功能性排便障碍经腰磁刺激运动诱发电位
functional defecation disordersmagnetic stimulationlumbar motor evoked potentials
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