慢传输型便秘的药物治疗新进展

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慢传输型便秘的药物治疗新进展

更新时间：2025-01-15

- 慢传输型便秘的药物治疗新进展
- Current pharmacologic therapies for chronic slow transit constipation
- 陆军军医大学学报 2013年35卷第21期页码：2259-2261
- 作者机构：
  
  中国医学科学院北京协和医学院，北京协和医院消化内科
- 作者简介：
- 基金信息：
- DOI：
  中图分类号： R975.3;R574.62
- 纸质出版日期：2013，
  
  网络出版日期：2013-11-15，
- 稿件说明：
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方秀才. 慢传输型便秘的药物治疗新进展[J]. 陆军军医大学学报, 2013,35(21):2259-2261.

FANG XIUCAI. Current pharmacologic therapies for chronic slow transit constipation. [J]. Journal of army medical university, 2013, 35(21): 2259-2261.
方秀才. 慢传输型便秘的药物治疗新进展[J]. 陆军军医大学学报, 2013,35(21):2259-2261. DOI：

FANG XIUCAI. Current pharmacologic therapies for chronic slow transit constipation. [J]. Journal of army medical university, 2013, 35(21): 2259-2261. DOI：

摘要

Abstract

Functional constipation

manifesting as infrequent bowel movements

hard or lumpy stools

is a disorder of colonic motility and slow transit function

as well as poor intestinal fluid secretion or over absorption. Short- and long-term clinical trials had been carried out to evaluate the efficacy and safety of a selective 5-HT

receptor agonist prucalopride

a chloride channel-2 activator lubiprostone

and a synthetic guanylate cyclase C agonist linaclotide on chronic constipation patients with infrequent bowel movements. These novel pharmacologic agents offered alternative options for the therapy of slow transit constipation when the patients got no satisfactory relief for their constipation symptoms from conventional laxatives.

关键词

功能性便秘慢传输型便秘药物治疗

Keywords

functional constipationslow transit constipationdrug therapy

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