Objective        To determine the clinical efficacy and safety of allografting and locked compression plating in the treatment of benign bone tumors and tumor-like lesions of the extremity.       Methods        From March 2005 to May 2011

56 patients in our department underwent radical curettage

allograft bone transplantation and locked compression plate fixation for benign bone tumors and tumor-like lesions of the extremity. They were 31 males and 25 females with a mean age of 38.7±3.6 years (ranging from 10 to 61 years). The types of primary tumors in these patients were bone cyst in 16 patients

bone fibrous dysplasis in 15

aneurysmal bone cyst in 10

bone giant cell tumor in 9

osteoblastoma in 3 and eosinophilic granulomatosis in 3 patients. Pathological fracture occurred in 36 patients. The volume of allograft bone

immunological rejection

bone reconstruction

healing time

and tumor recurrence were reviewed and analyzed.       Results        Besides 5 patients were lost for follow-up

the cohort of patients was followed up for a mean duration of 25.5±12.3 months (ranging from 12 to 60 month). The median bone mass were 23.5±10.3 g. Two patients had recurrence of bone giant cell tumor

and the others were cured totally. Four patients had complications as immunological rejection

with a mean bone healing time of 6 months. In 1 year after the first surgery

internal fixation was removed according to their bone healing

and no nonunion or re-fracture was observed.       Conclusion      Allograft bone implantation shows definite efficiency in promoting osteogenesis and repairing bone defect

with no obvious immunological rejection. It combined with locked compression plate

can be used to treat the benign bone tumors and tumor-like lesions of the extremity after curettage of lesions.