Objective      To investigate the correlation of aggressive behavior with coping styles

anxiety and depression in depressed patients.       Methods      Eighty patients with fist-episode and recurrent major depression from the out-patient and inpatient clinic in the department of psychiatry of our Fi

rst Affiliated Hospital of Chongqing Medical University during September 2010 to October 2011 and 80 healthy volunteers from the hospital staff and by recruitment advertising from October 2010 to November 2011 were recruited in this study. Participants were investigated by aggression questionnaire

the trait coping style questionnaire (TCSQ)

Hamilton depression rating scale (HAMD)

and Hamilton anxiety rating scale (HAMA). Then Spearman correlation and regression analysis were conducted to study the correlation of coping styles with anxiety symptoms

depression symptoms and aggressive behavior in patients with major depressive disorder.       Results      The scores of anger

hostility

self-aggression and total score of aggressive behavior were significantly higher in depression disorder patients than controls (P

<

0.01). Correlation analysis showed that the scores of physical aggression

verbal aggression

self-aggression

anger

hostility and total score of aggressive behavior were positively correlated with the score of negative coping styles (

r

=0.37 to 0.60

P

<

0.01)

and the scores of self-aggression and hostility and total score of aggressive behavior were negatively correlated with the score of positive coping style (

r

= -0.29 to -0.38

P

<

0.05). The scores of verbal aggression

anger

and total score of aggressive behavior were positively correlated with the total score of HAMA and HAMD (

r

=0.29 to 0.45

P

<

0.05). Negative coping styles had significant prediction function of 14.5% on physical aggression

32.9% on hostility

and 35.2% on self-aggression. Negative coping styles and the total score of depression had significant prediction role of 21.9% on verbal aggression. Negative coping style and the total score of anxiety paid a significant prediction role of 39.2% on anger

and 45.3% on the total score of aggressive behavior.       Conclusions      Patients with major depressive disorder have obviously aggressive behaviors

and the negative co

ping style maybe has an important role in the prediction and occurrence.