Onco-endocrinology Committee of Chinese Anti-Cancer Association. Chinese expert consensus on immune checkpoint inhibitors induced emergency management of endocrine adverse reactions[J]. Journal of chongqing medical university, 2023, 48(1): 1-12.
Onco-endocrinology Committee of Chinese Anti-Cancer Association. Chinese expert consensus on immune checkpoint inhibitors induced emergency management of endocrine adverse reactions[J]. Journal of chongqing medical university, 2023, 48(1): 1-12.DOI:
Immune checkpoint inhibitors (ICPis) are emerging anti-tumor drugs
with endocrine adverse reactions as its most common adverse drug reactions
and mainly involves multiple endocrine glands
such as glands of thyroid
pituitary
adrenal and pancreas
leading to endocrine dysfunction. If its emergencies can not be correctly identified and prevented in the early stage
it may be life-threatening. Although a number of relevant guidelines/consensuses have been published at home and abroad
there is no consensus on the diagnosis and treatment process of endocrine adverse reactions caused by ICPis in China. In order to standardize and improve the clinical diagnosis and treatment level of relevant departments
we have reviewed and analyzed a number of domestic and international expert consensuses and clinical studies
and formulated this consensus based on integration of the opinions of oncology