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收稿:2025-11-04,
修回:2026-03-16,
录用:2026-03-16,
纸质出版:2026-03-30
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子十儿童肿瘤专家组. 儿童及青少年横纹肌肉瘤诊治指南(2026年版)[J/OL]. 重庆医科大学学报, 2026,1-10.
.Guideline for the diagnosis and treatment of rhabdomyosarcoma in children and adolescents (2026 edition)[J].Journal of Chongqing Medical University,
子十儿童肿瘤专家组. 儿童及青少年横纹肌肉瘤诊治指南(2026年版)[J/OL]. 重庆医科大学学报, 2026,1-10. DOI:
.Guideline for the diagnosis and treatment of rhabdomyosarcoma in children and adolescents (2026 edition)[J].Journal of Chongqing Medical University, DOI:10.13406/j.cnki.cyxb..
横纹肌肉瘤(Rhabdomyosarcoma,RMS)是儿童期最常见的软组织肉瘤,约占儿童软组织肉瘤的40%。本病可发生于全身各部位,常见原发部位包括头颈部、四肢及泌尿生殖系统。其临床表现缺乏特异性,部分患儿确诊时已伴远处转移。目前,临床实践在风险分层、治疗规范化等方面仍存在不足,且近年来有新亚型。为此,本指南旨在系统介绍其病因、诊断、治疗与随访方案,为临床诊疗提供科学、规范的参考。临床应用中需结合患者具体情况个体化实施。
Rhabdomyosarcoma(RMS) is the most common soft tissue sarcoma in childhood,accounting for approximately 40% of pediatric soft tissue sarcomas. This disease can occur in any part of the body,with the common primary sites of the head and neck,the extremities,and the genitourinary system. Due to a lack of specific clinical manifestations,some children may present with distant metastases at the time of diagnosis. Current clinical practice still faces challenges in risk stratification and treatment standardization,while new subtypes have been reported in recent years. This guideline aims to systematically outline the etiology,diagnosis,treatment,and follow-up protocols for RMS and provide a scientific and standardized reference for clinical diagnosis and treatment. It should be implemented based on the specific conditions of each patient.
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