Objective     To evaluate the diagnostic values of procalcitonin (PCT)

C-reactive protein (CRP)

erythrocyte sedimentation rate (ESR)

blood platelet (PLT) and white blood cell count (WBC) for Kawasaki disease. Methods     A total of

161 children suspected to Kawasaki disease admitted in our hospital from March 2014 to February 2016 were enrolled in this study. They were examined for the levels of PCT

CRP

ESR

PLT and WBC. With the clinical symptoms and B ultrasound examination as the golden standard

92 cases of the 161 children (incomplete and atypical Kawasaki disease) were confirmed having Kawasaki disease

and the other 69 cases were excluded. Receiver operating characteristic curve (ROC) analysis was used to determine the diagnostic cut-off values. Results     The cut-off point was 0.25 ng/mL for PCT

8.04 mg/L for CRP

35 mm/h for ESR

330×10

9

/L for PLT

and 15.0×10

9

/L for WBC. The areas under ROC curves of PCT

PLT

CRP

ESR and WBC were 0.766

0.727

0.699

0.702

0.702 and 0.660 respectively in the Kawasaki disease diagnostic tests. The sensitivity

specificity

accuracy

positive and negative predictive values

positive likelihood ratio

negative likelihood ratio of parallel tests of PCT+ESR+PLT were 96.7%

30.4%

68.3%

65.0%

87.5%

1.33 and 0.19

respectively

and those of serial tests of PCT+ESR+PLT were 19.6%

95.7%

52.2%

85.7%

50.8%

4.01 and 0.86

respectively in the diagnosis of Kawasaki disease. Conclusion     The sensitivity

specificity

accuracy

positive and negative predictive values of PCT are closely related to those of CRP

and are better to those of ESR

PLT and WBC. The combined detection of PCT+ESR+PLT is of important value in the diagnosis of Kawasaki disease.