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纸质出版:2016
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季刚.特比萘芬联合半导体激光治疗甲癣102例疗效观察[J].陆军军医大学学报(原第三军医大学学报),2016,38(14):1694-1697.
Ji Gang.Efficacy of terbinafine combined with semiconductor laser for 102 cases of onychomycosis[J].J Amry Med Univ (J Third Mil Med Univ),2016,38(14):1694-1697.
目的 分析特比萘芬联合半导体激光治疗甲癣的临床疗效。 方法 选取我科2011年3月至2015年3月门诊就诊的甲癣患者共102例。按照患者接受的治疗方案,分为联合组和对照组。对照组口服盐酸特比萘芬片0.25 g,1次/d,连服12周。联合组在对照组治疗方案基础上,加用半导体激光照射治疗,每周2次,疗程相同。停药24周后,对比两组患者的临床疗效。 结果 与对照组比较,联合组治疗后病甲(指甲、趾甲)的指甲生长长度、甲分离、甲板增厚、甲板破坏程度和甲沟炎评分、甲真菌病临床评分指数差异有统计学意义(P0.05);联合组治疗后的总有效率、清除率高于对照组(100.00% vs 90.19%,54.92% vs 29.41%,P0.05)。 结论 特比萘芬联合半导体激光治疗甲癣具有较好的临床疗效。
Objective To analyze the clinical efficacy of terbinafine combined with semiconductor laser for onychomycosis. Methods A total of 102 outpatients with onychomycosis in our department from March 2011 to March 2015 were divided into a combination group and a control group. The control group was treated with terbinafine hydrochloride tablets
0.25 g qd
for 6 weeks. The combination group was added with semiconductor laser irradiation treatment
twice a week for 6 weeks. The clinical efficacy was compared between the 2 groups. Results After treatment
the growth length of fingernail and toenail in the combination group was significantly improved (P0.05)
and the deck thickness
deck damage extent
paronychia score and scoring of clinical index for onychomycosis (SCIO) had statistically significant differences compared with the control group (P0.05). The total efficiency and clearance rate of the combined group after treatment was higher (100.00% vs 90.19%
54.92% vs 29.41%
P0.05). Conclusion Terbinafine combined with semiconductor laser has good clinical efficacy for onychomycosis.
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