Objective      To investigate the diagnosis and treatment method for spontaneous cerebrospinal fluid (CSF) rhinorrhea with intranasal endoscopy.       Methods      Clinical data of 7 cases with spontaneous CSF rhinorrhea who underwent intranasal endoscopic repair in our hospital from 2000 to 2014 was analyzed retrospectively. They were 2 males and 5 females

at a mean age of 41 (ranging from 19 to 64)

and had suffered from the disease for average 8 months (ranging from 3 to 15 months). The clinical features

body mass index (BMI)

pressure of CSF

image data

transnasal endoscopic ex

amination

surgical treatment and follow-up data were reviewed and analyzed.       Results      All the patients had been failed with 2 weeks’ conservative treatment

and had to underwent surgical treatment. They were cured by successful surgical repairing under nasal endoscope except 1 patient experienced the operation twice.   The intracranial pressure was measured in 1 month after operation by lumbar puncture

the CSF pressure was 64.1~198.5 mmH

2

O

and the average was 135.5 mmH

2

O. The intracranial pressure was measured in 3 months after operation

and the CSF pressure was 105.7~203 mmH

2

O

and the average was 189.8 mmH

2

O.During the follow-up for 6 months to 7 years

no recurrence was found in the cohort.       Conclusion      Transnasal endoscopy

CT scanning

and MRI are main diagnostic methods to diagnose spontaneous CSF rhinorrhea and make an accurate location of the defect. Transnasal endoscopic management has advantages of less trauma

rapid recovery

fewer complications

and higher successful rate. Accurate location of the defect

appropriate repair method and postoperative management of intracranial pressure are of great importance for successful treatment of CSF leak.