Objective      To investigate the value of Fuji intelligent chromoendoscopy (FICE) in the prediction of the depth of invasion in early esophageal carcinoma.       Methods      Totally 224 patients with esophageal mucosa lesions admitted in Chongqing Cancer Hospital from January 2011 to May 2014 were enrolled in this study. They all underwent FICE combined with magnifying endoscopy and miniature ultrasonic probe(MPS) to detect the lesions and the depth of invasion. The obtained results were compared with histopathological results.       Results      The correct rate of FICE combined with magnifying endoscopy was significantly higher than MPS in evaluation of early esophageal cancer invasion depth (P0.05)

and was consistent to the results of postoperative pathological examination (P0.01). FICE combined with magnifying endoscopy had high sensitivity and specificity in the judgement of whether cancer breakthrough in the middle of 1/3 of esophageal submucosa (sm2).       Conclusion      FICE is simple

intuitionistic to display images

and of good visualization when combined with magnifying endoscopy. So it has a real good authenticity in diagnosis of the depth of invasion of esophageal diseases.