The prevalence of erectile dysfunction (ED) is as high as about 50% in males

of which organic diseases take up 50%

and its severity is associated with the degree of tissue damage. Current management for ED consists of oral phosphodiesterase type 5 inhibitors (PDE5is)

intracavernosal injection therapy with vasodilating agents

and vacuum devices. However

these therapies are usually taken on demand just prior to the sexual activity

and can not alter the underlying pathophysiology of erectile tissue. Convergence medicine is defined as the merging of engineering

physical sciences and life sciences into a unity that provides different kinds of tools for the benefit of human health

and it is called the third revolution in the field of life science research

following the birth of molecular biology (the discovery of the structure of DNA in 1953) and the birth of genomics (the completion of the human genome project in 2001). Currently

as successful examples in the convergence medicine

low-energy shock wave therapy (LESWT) and low-intensity pulsed ultrasound (LIPUS) in the treatment of ED bright a new era to men’s healthcare.