Objective       To analyze the prevalence of HIV/AIDS in the high-risk population in Chongqing during the years of 2006 to 2012 so as to provide scientific basis for the intervention strategies of high-risk peoples.       Methods       The time series data were collected from infectious disease system and HIV monitoring sentinel. The estimation indicators were new HIV infections

HIV infection rate and condom usage rates. The overall rate and its 95% confidence interval (95%CI) were estimated based on Poisson distribution principle. The time serial correlation analysis was employed for time serial trend test.       Results       From 2006 to 2012

the main HIV infection routes were intravenous drug use

and heterosexual and homosexual transmission routes. The annual average HIV infection rates of the female sex workers (FSWs)

injecting drug users (IDUs)

men who have sex with men (MSM) and the people with sexually transmitted diseases (STDs) were 0.18% (95%CI: 0.10%-0.25%)

8.42% (95%CI: 7.82%-9.03%)

15.62% (95%CI: 14.41%-16.86%)

and 1.58% (95%CI: 1.25%-1.91%).The condom usage rates were 74.01% (95%CI: 73.21%-74.82%) and 62.30% (95%CI: 60.67%-63.92%) respectively for FSWs and MSM.       Conclusion       Chongqing should strengthen the intervention among FSWs

MSM

and STDs

and enhance the publicity of the importance of condom usage in MSM and FSWs.