Objective      To study the cognitive and motor function impairment in infants with different types of congenital heart disease (CHD).        Methods      Totally

164 infants with CHD were collected from our hospital during January 2009 to February 2014

and divided into a cyanosis group (n=31) and a non-cyanosis group (n=133) according to the presence or absence of cyanosis

and meanwhile

divided into the simple group (n=103) and the complex group (n=61) according to the heart malformation degree. At the same time

110 health neonates were selected as the control group. The cognitive and motor functions were assessed by Bayley scales of infant development (BSID).        Results      The mental development index (MDI) and psychomotor development index (PDI) of the infants with CHD were lower than those of the health neonates (P0.01). The MDI and PDI were lower in the cyanosis group than in the non-cyanosis group (P0.01)

and lower in the complex group than in the simple group (P0.05).        Conclusion      The incidence of cognitive and motor function impairment appears in the infants with CHD before three years-old

and the infants with cyanosis and complex type show relatively high impairment degree.