Objective      To quantitatively evaluate the left ventricular diastolic function in patients with hypertrophic cardiomyopathy (HCM) by cardiac magnetic resonance (CMR).       Methods      From October 2013 to August 2014

26 HCM patients (43.54±13.29 year-old in average; 15 males) and 28 healthy persons (41.52±11.87 year-old in average; 16 males) as control were enrolled as the HCM group and the control group

respectively. All the subjects underwent CMR examination to assess the cardiac structure and function. The correlations of left ventricular mass (LVM) with the left ventricular diastolic function parameters including left ventricular peak filling rate (LVPFR)

left atrial anteroposterior diameter (LAAPD)

left atrial superoinferior diameter (LASID) and left atrial transverse diameter (LATD) were analyzed.       Results      Compared with the control group

the LVM

interventricular septal thickness (IVS)

LAAPD

LASID and LATD increased significantly in the HCM group (P0.05)

while the LVPFR decreased obviously (P0.05). The systolic function parameters

such as left ventricular ejection fraction (LVEF) and left ventricular peak ejection rate (LVPER)

showed no significant differences between the two groups (P0.05). In the HCM group

LVM had significant negative correlation with LVPFR (r=-0.509

P0.05) and positive correlation with LAAPD and LATD (r=0.493 and 0.466

respectively

P0.05).       Conclusion      In HCM patients

the left ventricular diastolic function is significantly impaired

and LVM is closely related to LVPFR and left atrial diameter. CMR plays an important role in quantitatively evaluating the left ventricular diastolic function in the HCM patients.