Objective      To analyze the clinical characteristics of patients with hydronephrosis caused by diabetes insipidus.       Methods      Clinical data from 10 patients with diabetes insipidus causing bilateral ureter dilatation and bilateral hydronephrosis in our hospital from January 2011 to July 2014 were retrospectively analyzed

and the law of diagnosis and treatment was summarized.       Results      Polyuria

polydipsia symptom

urine specific gravity

urine osmotic pressure

water deprivation vasopressin test

and minirin diagnostic treatment had diagnostic values for diabetes insipidus. Central diabetes insipidus was treated with desmopressin acetate tablets

and nephrogenic diabetes insipidus was treated with natriuretic drugs plus drinking water restriction and timed urination to reduce the volume of the produced urine and ultimately improve the hydronephrosis.       Conclusion      Diabetes insipidus usually has longer course of disease and high misdiagnosis rate

and correct diagnosis helps to reduce unnecessary surgical intervention. Anti-diuretic therapy is effective for alleviating urinary tract dilatation and hydronephrosis caused by diabetes insipidus.