Objective      To evaluate the mechanical properties and bio-safety of carbon ion implanted silicone rubber (C-SR).       Methods      According to the national standard

the mechanical properties were measured with a Shore durometer (type A) and an electronic universal testing machine to obtain parameters including Shore A hardness

tensile strength

elongation at break and tear strength. The bio-safety was evaluated by erythrocyte hemolysis test

systemic toxicity test

subcutaneous implant test

allergic and dermal irritation test

and pyrogenic test.       Results      The evaluation results showed that the C-SR had the same mechanical properties as pure SR. The erythrocyte hemolysis test showed that the hemolysis rate of C-SR was lower than the national standard

which indicated that in vivo transplantation of C-SR could not cause the hemolytic reaction of the body. The systemic toxicity test results showed that C-SR had no toxicity. The subcutaneous implant test indicated that C-SR had good safety and compatibility in the body. The allergic and dermal irritation test result was zero

the same as the negative control

suggesting that C-SR had no allergic and dermal irritation. In the pyrogenic reaction

the body temperature of rabbits averagely increased by 0.1 ℃

indicating that C-SR had no pyrogenic effect

in accordance with the demands of medical materials.       Conclusion      The carbon ion implantation does not change the mechanical properties of SR

and C-SR has good bio-safety.