Objective        To observe the hemostatic function of biological glue in partial nephrectomy in rabbits in order to improve hemostatic efficiency in urological operation.       Methods        Fourteen rabbits were randomly divided into biological glue group (group A

n=7) and conventional suture group (group B

n=7). After the partial nephrectomy model was established on the left kidney

biological glue and conventional suture were used respectively to treat the wound. The volume of bleeding and bleeding time were observed and recorded. Tissue sample were transected from the wound of left kidneys in 1 month after the surgery

and the renal wound healing were observed and evaluated by the results of pathological examination.       Results        Compared with conventional suture group (group B)

significantly fewer bleeding volume (2.13±0.66 vs 5.57±1.43 mL

P0.01) and shorter bleeding time (5.55±1.62 vs 63.70±5.90 s

P0.01) was observed in biological glue group. Pathological observation indicated that the wound healed well in biological glue group

with less infiltration of chronic inflammatory cells than in conventional suture group.       Conclusion        Biological glue is significantly superior to conventional suture in hemostasis for partial nephrectomy

and is worth of promoting in clinical practice.