Objective     

To evaluate the central anterior chamber depth (CACD) before and after laser peripheral iridoplasty (LPI) in patients with primary angle-closure glaucoma (PACG)

and assess the difference

relevance and consistency between Pentacam and slit-lamp-adapted optical coherence tomography (SL-OCT) in measuring CACD.       Methods      A total of 58 PACG patients (58 eyes) were enrolled in this study. Pentacam anterior segment analysis system and Heidelberg SL-OCT were used separately before and in 1 d

1 week

and 1 month after LPI to measure the CACD in all patients.       Results      The mean CACD values of PACG before and in 1 d

1 week

and 1 month after LPI measured by Pentacam were 1.60±0.31

1.65±0.28

1.62±0.30

and 1.61±0.31mm

respectively

while those measured by SL-OCT were 1.70±0.30

1.73±0.30

1.71±0.31

and 1.72±0.31 mm

respectively. Using the 2 methods

no statistical differences was observed in the CACD values before and after LPI in PACG (

P

0.05). Significant differences of CACD values

however

existed between the 2 methods at all time points (

P

0.01). Good correlations were found between Pentacam and SL-OCT before and in 1 d

1 week

and 1 month after LPI (r=0.929

P

0.001; r=0.962

P

0.001; r=0.961

P

0.001; and r=0.951

P

0.001

respectively). By Bland-Altman analysis

the 95% limits of differences between Pentacam and SL-OCT before and in 1 d

1 week

and 1 month after LPI were -0.33 to 0.12

-0.29 to 0.08

-0.25 to 0.08

and -0.26 to 0.07 mm

respectively.       Conclusion      In PACG

Pentacam and SL-OCT

of good consistency and correlation in measuring CACD

can be both used for glaucoma screening

and provide an effective non-invasive and quantitative way for patients.