Objective      To investigate the awareness

experience and willingness of using HIV pre-exposure prophylaxis (PrEP) among men who have sex with men (MSM)

and to study the predictors of the willingness to use PrEP.        Methods      A total of 1 407 MSM were recruited from Chongqing

Sichuan

and Guangxi to complete an anonymous

structural quantitative survey

with 1 402 qualified questionnaires analyzed. Descriptive analysis was conducted for the awareness

experience and willingness of using PrEP. Predictors of willingness to use PrEP were analyzed by logistic regression.        Results      Of all the participants

22.1% (95%CI: 20.0% to 24.3%) reported that they had previously heard of PrEP. No participant reported definite PrEP use. The results indicated that 63.6% (95%CI: 61.0% to 66.1%) of participants were willing to use PrEP in the future if it was proven safe and effective. The predictors of willingness to use PrEP included lower education

moderate income compared with the lowest income

never or rarely finding sex partners on the Internet

sexually transmitted infection (STI) history

more knowledge of AIDS

being worried about HIV as a threat to themselves and their family

hearing about PrEP previously

and perception of PrEP efficacy.       Conclusion      The awareness of PrEP among MSM in Western China is modest

but the high interest in using PrEP suggests that implementing and promoting PrEP in this population is feasible.