Wang Peng,Xiao Hong,Pang Xueli.Preliminary investigation on treatment modes of pineal region tumors in Western China[J].J Amry Med Univ (J Third Mil Med Univ),2013,35(20):2216-2219.
Wang Peng,Xiao Hong,Pang Xueli.Preliminary investigation on treatment modes of pineal region tumors in Western China[J].J Amry Med Univ (J Third Mil Med Univ),2013,35(20):2216-2219.DOI:
Objective To investigate and analyze the treatment modalities in large hospitals in Western China in order to provide basis for establishing clinical guidelines for the treatment of pineal region tumors. Methods Retrospective analysis of pineal region tumor treatment data of 9 top
large hospitals in Western China was carried out
focusing on the treatment options such as surgery
radiation therapy
their sequence
specific procedures and so on. Results A total of 219 patients’ medical records were collected
of which 58 were treated with surgery and 196 with radiotherapy. In the surgical group
tumor complete resection in 52 cases and subtotal tumor resection in 6 cases were found. The radiotherapy group included 99 cases treated after ventriculo-peritoneal shunt or three ventriculostomy
58 cases of direct radiotherapy
and 39 cases of tumor resection surgery followed by radiotherapy. As for the radiotherapy pattern
it was found that 153 cases were treated with stereotactic radiotherapy technique
43 cases with linear accelerator radiation
of which 25 with diagnostic radiotherapy
and 21 cases with whole central nervous system radiation. Conclusion Radiotherapy after ventriculo-peritoneal shunt/three ventriculostomy is the most common treatment mode of pineal region tumor
followed by tumor resection plus radiotherapy. There are huge differences in the selection of radiotherapy techniques and doses. The results indicate a lack of specification in the treatment of pineal region tumors in Western China. It is important and urgent to give much concern for the establishment of diagnosis and treatment standard.