Objective      To investigate the clinical features of salivary gland pleomorphic adenoma and its manifestation of multi-slice spiral computed tomography (MSCT）to promote its diagnostic accuracy for surgery.       Methods      Clinical data and MSCT images of 47 cases with pathology-confirmed salivary gland pleomorphic adenoma undergoing surgery in our hospital from January 2011 to August 2012 were collected and retrospectively analyzed in this study.       Results      In these 47 cases

89.4%（42/47）were solitary lesion

and 10%（5/47）were multiple lesions in one side; 59.6% （28/47）were located in the parotid gland

17.0%（8/47） in the submandibular gland

14.9%（7/47） in the pars palatalis and 8.5%（4/47） in the bucca. During the surgery

27.7%（13/47）lesions were found to be adhered to the peripheral structure

10.6%（5/47） lesions had incomplete envelope

and 19.1%（9/47）lesions had nodules on the surfaces. On MSCT images

most gland pleomorphic adenomas were well-defined and iso-density masses

in a round or round-like shape. There were 14.9%（7/47）cases with cystic degeneration

commonly in the postoperative recurrent or multiple cases

and 6 from them was located in the parotid gland. No cystic degeneration was found in the parotid gland and submandibular gland. There were 95.7%（45/47）cases showing delayed reinforcement (delayed 180 s). For the 4 cases in the hard palate

because of its unique anatomical structure

three-dimensional reconstruction techniques

volume render (VR) and multiplanar reconstruction （MPR）

were used to not only enhance the detection rate but also manifest the location

shape

size and change of the adjacent regions clearly.       Conclusion      MSCT manifestation of salivary gland pleomorphic adenoma is of specificity. For the lesion located in the hard palate

it is usually very small. Three-dimensional reconstruction techniques should be carried out routinely combined with clinical data to improve preoperative diagnostic ratio.