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纸质出版:2013
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杜伟,甘承文,郭海波,许路,程佳,单幼兰.重庆市某研究所体检人群中维生素D水平的调查研究[J].陆军军医大学学报(原第三军医大学学报),2013,35(07):676-678.
Du Wei,Gan Chengwen,Guo Haibo,Xu Lu,Cheng Jia,Shan Youlan.Serum level of 25 (OH) vitamin D among normal population in Chongqing[J].J Amry Med Univ (J Third Mil Med Univ),2013,35(07):676-678.
目的 了解重庆地区健康人群维生素D(VitD)营养状况。 方法 用串联质谱分析仪检测送检人员血清25-羟维生素D[25(OH)VitD]水平,据此确定VitD营养状况。随机抽取重庆金域医学检验所从2012年1-8月的体检健康人员共3 875例,3~71岁。按年龄分为≤14岁儿童组(657例)、15~44岁青壮年组(3 019例)和≥45岁中老年组(199例)3组,采用SPSS 13.0统计软件进行数据分析。 结果 年龄≤14岁组的25(OH)VitD水平严重缺乏、缺乏、不足、正常、过量所占的比例分别为1.52%、19.03%、9.44%、70.02%和0%;15~44岁组水平缺乏、不足、正常、过量的比例分别为60.09%、27.59%、12.32%和0%;≥45岁组水平缺乏、不足、正常、过量的比例分别为84.92%、13.07%、2.01%和0%。15~44岁组和≥45岁组女性25(OH)VitD平均水平均较男性低,缺乏的女性人数较男性所占比例高,差异均有统计学意义(P0.01),而≤14岁组男女间差异无统计学意义;≥45岁组与15~44岁组相比,25(OH)VitD平均水平随着年龄增加而降低,差异有统计学意义(P0.01)。 结论 重庆地区人群VitD不同程度缺乏,女性缺乏所占比例较男性高,儿童有严重缺乏。
Objective To investigate the nutritional status of Vitamin D (VitD) among the normal population in Chongqing. Methods Three thousand eight hundred and seventy-five health people with age from 3 to 71 years
who were collected from Chongqing Kingmed Diagnostics from January to August 2012 were enrolled in this study. They were divided into 3 groups according to their age
that is
≤14-year-old group (n=657)
15- to 44-year-year-old group (n=3 019)
and ≥45-year-old group (n=199). Their serum level of 25 (OH) VitD was detected by API4000Lc-MS/MS. Software SPSS 13.0 was used for statistical analysis. Results In ≤14-year-old group
the ratios of those with VitD severe deficiency
deficiency
insufficient
normal
and excess were 1.52%
19.03%
9.44%
70.02% and 0%
respectively. In the 15- to 44-year-old group
the ratios of 4 later statuses were 60.09%
27.59%
12.32% and 0%
respectively
while the ratios were 84.92%
13.07%
2.01% and 0% respectively for the ≥45-year-old group. In the 2 later groups
the females had lower level of VitD than the males
and had higher ratio of VitD deficiency at the same time (P0.01)
but no such difference was found in the ≤14-year-old group. The average serum level of VitD was decreased along with the increase of age in the ≥45-year-old group compared with the 15- to 44-year-year-old group (P0.01). Conclusion The different degree of VitD deficiency exists in the population of Chongqing area (including children). Women have a higher proportion with VitD deficiency. There is roughly equal ratio of VitD deficiency between girls and boys among the children
but the deficiency is serious.
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