Objective　　　To explore the clinical value of 320-row CT upper abdominal one-stop examination in transcatheter arterial chemoembolization(TACE) treatment for hepatocellular carcinoma (

HCC).　　　 Methods　　　Totally 30 patients with HCC underwent upper abdominal perfusion scanning with 320-row CT before TACE. The whole liver perfusion was analyzed

and the angiography capability of 320-row CT scan was compared with that of digital subtraction angiography (DSA) in TACE. Cancer tissue perfusion was followed up after operation and was compared with that before operation. The radiation doses of 320-row CT perfusion scan were also analyzed.　　　 Results　　　 There were significant differences in hepatic arterial perfusion (HAP)

portal vein perfusion (PVP) and hepatic arterial perfusion index (HAPI) between cancer tissues and non-cancerous tissues before TACE (P0.05). Cancer necrotic tissues had no blood perfusion after TACE. Higher HAP and PVP and lower HAPI were observed in active cancer tissues after operation as compared with those before operation

while higher HAP and HAPI and lower PVP were observed in active cancer tissues as compared with the non-cancerous tissues after operation. Those differences were statistically significant. Satisfactory upper abdominal computer tomography angiography (CTA) images were obtained in all the 30 scans. The comparison between 1-4 grade hepatic artery CTA and DSA had no significant difference (

P

0.05)

while the comparison between 5 or more than 5 grade CTA and DSA confirmed significant difference (

P

0.01). Perfusion scan with lower parameter (100 kV

100 mA) had lower radiation dose than the conventional upper abdomen enhanced scan did

while that with higher parameter (100 kV

200 mA) only had slightly higher radiation dose.　　　 Conclusion　　　320-row CT upper abdominal one-stop examination can display the whole liver perfusion well

especially the abnormal perfusion of hepatocellular carcinoma tissues and postoperative active tissues. Angiography can display the hepatic arteries and nutrient arteries of tumors from three dimensions

and has important guiding significance in preoperative evaluation

surgery operation and postoperative follow up of TACE.