Objective      To study the diagnostic value of capsule endoscopy for gastrointestinal diseases.       Methods      Clinical data about 663 patients (including 176 health volunteers) who underwent OMOM capsule endoscopy of gastrointestinal diseases were retrospectively analyzed. Their lesions and images

and the safety of and tolerance to capsule endoscopy were observed.       Results      Of the 663 patients

658 completed the capsule endoscopy with a success rate of 99.2%

528 were found to have 1 121 lesions including 403 who were found to have 2 or more than 2 lesions with a detection rate of 79.6%

487 were found to have intestinal lesions with a detection rate of  61.8% and a diagnostic rate of 55.0%. The detected lesions were erosion

ulcer

polypus

angiodysplasia

diverticulum

parasites

lymphangiectasis and tumor. The average running time of capsules in the esophagus was 3-58 s（28.2±11.8 s）. The running time of capsules in the stomach and small intestine was 2-204 min (57.4±48.4 min) and 54-525 min (268.7±96.9 min)

respectively. Capsule retention was observed in 4 patients.       Conclusion      Capsule endoscopy is a safe and effective procedure for gastrointestinal diseases with a good tolerance and a high diagnostic rate

and is thus of important diagnostic value for gastrointestinal diseases

especially for small intestinal diseases.