Objective      To investigate influencing factors of high intraocular pressure (IOP) during stable period (1 to 3 months) after implantable collamer lens (ICL) and therapeutic efficacy.        Methods      Clinical data of 79 high myopia patients (155 eyes) who received ICL from January to December in 2011 were analyzed retrospectively. They were 36 males and 43 females

with an age ranging from 18 to 46 (mean 23.84±6.54)

and were followed up within 6 months post-operatively. IOP

uncorrected visual acuity

best corrected visual acuity

refractive diopter

slit lamp examination

gonioscopy

coneal endocellion

central anterior chamber depth (ACD)

lens thickness

axial length

vault and trabecular-iris angle (TIA) were observed and analyzed.        Results      Eight patients （16 eyes） experienced high IOP during stable period post-operatively with an incidence of 10.32% (16/155). Non-high IOP after ICL was found in 71 patients (139 eyes). Fourteen eyes (87.5%) out of 16 eyes were treated with drops and good outcomes were obtained

but the left 2 eyes (12.5%) had to turn to surgery which were uncontrollable with drops. Pre- and post-operative ACD

post-operative vault and TIA were closely related to high IOP during stable period after ICL（P0.05

P0.01）. Post-operative TIA was an independent influencing factor for high IOP after ICL. IOP and best corrected visual acuity (BCVA) were 26.13±3.56 mmHg and 0.69±0.20 in stable period

19.98±2.51 mmHg and 0.80±0.19 in 1 week after treatment

and 17.58±2.30 mmHg and 0.84±0.19 at the end of follow-up. There were significant difference between those of the stable period with those of later 2 time points（P0.05

P0.01）.        Conclusion      High IOP during stable period after ICL may be related to not matching good enough between ICL and eye ball

which induces chronic inflammation for long time.