Objective      To investigate the feasibility and safety of gastroscopic-assisted laparoscopic resection in treatment of gastric stromal tumors.       Methods      The clinical data of 16 patients with gastric stromal tumors treated with gastroscopic-assisted laparoscopic resection from Mar. 2008 to Oct. 2011 were analyzed. Fourteen patients were treated by gastroscopic-assisted laparoscopic wedge resection

1 patient was treated by gastroscopic-assisted laparoscopic transluminal resection

and 1 patient was treated by laparoscopic-assisted gastroscopic resection.       Results      All the operations were successful

and no peritoneotomy conversion and complication occurred. The operation time was (80.3±23.7) min

the blood loss during operation was (20.4±11.6) ml

and the postoperative hospital stay was (5.6±2.1) d. The resected tumor was 1.3 to 2.7 cm in diameter. The immunohistochemical results showed that 12 patients were CD117-positive (75.0%) and 9 patients were CD34-positive (56.2%). There were 11 patients with extremely low risk

5 patients with low risk and no patient with high risk.       Conclusion      Gastroscopic-assisted laparoscopic resection in treatment of gastric stromal tumors is safe and feasible

but its long-term effect need to be further analyzed．