Objective      To explore the short-term efficacy of Artecoll on removing faciocervical wrinkles.       Methods      A total of 629 patients who received Artecoll injection to remove wrinkles in the Department of Plastic and Aesthetic Surgery of Southwest Hospital from January 2004 to December 2010 were enrolled. The patients included 45 males and 584 females with an average age of 43.5 (28-64) years old. According to different faciocervical injection sites

the 629  patients were divided into six groups including nasolabial fold (305)

glabellum (182)

neck (37)

frontal part (54)

canthus (32) and bridge of nose (19). The short-term efficacy of Artecoll was analyzed at the injection day and 1 month

3 months

6 months and 1 year after injection.       Results      All faciocervical wrinkles were removed or significantly removed at the injection day. The effect maintained after 1 month

and gradually diminished after 3 to 6 months. The wrinkle removing effect after 12 months was still significant as compared with that before Artecoll injection. The short-term effects of wrinkle removal on nasolabial fold

glabellum

bridge of nose and neck were better than those on frontal part and canthus.       Conclusion      Artecoll injection for removing faciocervical wrinkles is a newly developed technique and has a high patient satisfaction degree according to our experiences. It is one of the optimal therapies for wrinkle removal.