发作间期/发作期SPECT rCBF显像在癫痫灶定位诊断中的价值

杨雅娜; 罗焱; 胡云; 苏红媛; 杨辉; 张青

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发作间期/发作期SPECT rCBF显像在癫痫灶定位诊断中的价值

论著 | 更新时间：2026-01-09

- 发作间期/发作期SPECT rCBF显像在癫痫灶定位诊断中的价值
- Value of interictal/ictal single photon emission computed tomography regional cerebral blood flow imaging in localization of epileptic foci
- 陆军军医大学学报 2012年34卷第11期页码：1107-1110
- 作者机构：
- 作者简介：
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  中图分类号： R741.049;R749.17;R814.4
- 纸质出版：2012
- 稿件说明：
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杨雅娜,罗焱,胡云,苏红媛,杨辉,张青.发作间期/发作期SPECT rCBF显像在癫痫灶定位诊断中的价值[J].陆军军医大学学报(原第三军医大学学报),2012,34(11):1107-1110.

　Yang Yana,Luo Yan,Hu Yun,Su Hongyuan,Yang Hui,Zhang Qing.Value of interictal/ictal single photon emission computed tomography regional cerebral blood flow imaging in localization of epileptic foci[J].J Amry Med Univ (J Third Mil Med Univ),2012,34(11):1107-1110.
杨雅娜,罗焱,胡云,苏红媛,杨辉,张青.发作间期/发作期SPECT rCBF显像在癫痫灶定位诊断中的价值[J].陆军军医大学学报(原第三军医大学学报),2012,34(11):1107-1110. DOI：

　Yang Yana,Luo Yan,Hu Yun,Su Hongyuan,Yang Hui,Zhang Qing.Value of interictal/ictal single photon emission computed tomography regional cerebral blood flow imaging in localization of epileptic foci[J].J Amry Med Univ (J Third Mil Med Univ),2012,34(11):1107-1110. DOI：

摘要

目的探讨发作间期/发作期SPECT局部脑血流灌注显像(regional cerebral blood flow，rCBF)在癫痫术前定位诊断中的价值。方法回顾性分析第三军医大学新桥医院神经外科行外科手术治疗的115例癫痫患者，术前分别行发作间期/发作期SPECT显像、常规脑电图（electroencephalogram，EEG）、视频脑电图（vedio-EEG，VEEG）、CT或MRI检查，术中行皮层脑电图（electrocorticogram，ECoG）监测，与发作间期/发作期SPECT、EEG、VEEG、CT和MRI检查结果进行比较分析。结果发作间期/发作期SPECT检出癫痫的阳性率为90.4%，高于EEG的37.4%(P0.05)、VEEG的82.6%(P0.05)、CT的48.8%(P0.05)和MRI的54.2%(P0.05)。与术中ECoG结果比较，发作间期/发作期SPECT对癫痫灶定侧率为91.3%，定位率为71.2%。结论术前发作间期/发作期SPECT显像与ECoG在癫痫灶定位诊断上具有较高的一致性，在术前综合定位诊断中具有重要意义。

Abstract

Objective To study the value of interictal/ictal single photon emission computed tomography (SPECT) regional cerebral blood flow (rCBF) imaging in localization of epileptic foci. Methods Interictal/ictal SPECT

EEG

VEEG

CT or MRI

and ECoG of 115 epilepsy patients

who underwent operation in Department of Neurosurgery

Xinqiao Hospital

Third Military Medical University

were retrospectively analyzed and compared. Results The positive detection rate of interictal/ictal SPECT for epilepsy was higher than that of EEG

VEEG

CT and MRI (90.4% vs 37.4%

82.6%

48.8% and 54.2%

P0.05). The localization rate of interictal/ictal SPECT for epileptic foci was higher than that of ECoG (91.3% vs 71.2%

P0.05). Conclusion The interictal/ictal SPECT is highly consistent with ECoG in localization of epileptic foci

thus playing an important role in preoperative localization of epilepsy.

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