Objective      To study and evaluate the risk factors of mother-to-child transmission of hepatitis B virus (HBV).       Methods      The relationships of gestational weeks

delivery modes

peripheral blood HBV DNA levels and feeding ways with mother-to-child transmission of HBV were retrospectively analyzed in 163 HBsAg-positive pregnant women from 2007 to 2011.       Results      The rate of mother-to-child transmission of HBV was 4.29% (7/163) after routine preventive inoculation. The peripheral blood HBV DNA level in the pregnant women was positively correlated with the cord blood HBV DNA level in newborn infants and the venous blood HBV DNA level in during infants follow-up (P0.05). The cord blood HBV DNA level in newborn infants was significantly related to the venous blood HBV DNA level in 6-month-old infants (P0.05). Gestational weeks

delivery modes and feeding ways were not related to mother-to-child transmission of HBV (P0.05).       Conclusion      Delivery modes and feeding ways are low risk factors

and the maternal peripheral blood HBV DNA level is a high risk factor for mother-to-child HBV transmission

which can not be reduced by cesarean section or increased by breast feeding and mixed feeding.