Objective      To investigate the efficacy and complications of lauromacrogol injection endoscopic sclerotherapy in treatment of esophageal varices.       Methods      Retrospective analysis was performed in 64 patients with esophageal varices (forty-six males and eighteen females

with the mean age of 48.6±14.0 years old) who underwent a total of 153 times of lauromacrogol injection sclerotherapy in the endoscopy center from May 2009 to December 2010. The rates of emergent hemostasis

complete and nearly complete elimination of esophageal varices

and the mortality and the incidence of complications were observed. Clinical data were collected from outpatient and telephone follow-up from 1 month to 17 months after injection.       Results      The rate of hemostasis in the whole group was 94.4%. The incidence of complications was 2.0% to 23.5%. The rate of complete and nearly complete elimination of esophageal varices was 80%. The mortality was 1.6%.       Conclusion      Lauromacrogol injection endoscopic sclerotherapy has good efficacy and few complications in treatment of esophageal varices and is safe in clinical application.